Evidence map›Paper›PMID 37817851›Full record

ArticleAnnals of cardiothoracic surgery2023

Safety of cerebrospinal fluid drainage in descending and thoracoabdominal aortic replacement surgery.

Afsheen Nasir, Mohammad A Zafar, Mohamed Abdelbaky, Dimitra Papanikolaou, Hesham Ellauzi, Maryam Shaikh, Bulat A Ziganshin, John A Elefteriades

Open access · diamondAbstract read
In one paragraph

Article in Annals of cardiothoracic surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Afsheen NasirAortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT, USA.
Mohammad A ZafarAortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT, USA.
Mohamed AbdelbakyAortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT, USA.
Dimitra PapanikolaouAortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT, USA.
Hesham EllauziAortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT, USA.
Maryam ShaikhAortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT, USA.
Bulat A ZiganshinAortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT, USA.
John A ElefteriadesAortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT, USA.
Yale New Haven Hospital · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

Background: Spinal cord injury (SCI) remains a significant morbidity of surgical repair of descending thoracic aortic aneurysms (DTAA) and thoracoabdominal aortic aneurysms (TAAA). We present our 17-year experience with cerebrospinal fluid drainage (CSFD) as a protective strategy during open surgical repair of descending and thoracoabdominal aortic disease. Methods: We conducted a retrospective chart review of 132 patients who underwent open surgical repair of DTAA and TAAA and dissections with concurrent use of CSFD for spinal cord protection. Information regarding survival, postoperative course, and complications related to CSFD use were extracted from electronic health records (EHR) and analyzed. Results: Mean patient age was 65.4±13.0 years, and 82 (62.1%) were male. A CSFD was successfully inserted in all patients. The mean hospital length of stay after surgery was 12.2±11.2 days, and in-hospital mortality was 7.6%. Postoperative transient paresis was observed in 5 patients (3.8%), and permanent paraplegia was seen in 4 (3.0%). CSFD related complications were reported in 25 patients (19%). Complications included persistent cerebrospinal fluid (CSF) leakage, blood-tinged CSF (with subdural hematoma reported in 3 patients) and spinal cutaneous fistula in 9 (7%), 14 (11%), and 1 (1%), respectively. Long term survival was 50.9% at 15 years. Conclusions: CSFD is associated with minor complications, without major sequalae. It is a safe practice and likely contributes innocuously to decreased SCI in patients undergoing open repair of DTAA and TAAA.

Indexed as

spinal cord protectionSpinal drainthoracic aortic repair

Identifiers

PMID37817851
PMCPMC10561341
OpenAlexW4386968669

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.