Evidence map›Paper›PMID 37817764›Full record

ArticleFrontiers in oncology2023

Revolutionizing anti-cancer drug discovery against breast cancer and lung cancer by modification of natural genistein: an advanced computational and drug design approach.

Shopnil Akash, Shabana Bibi, Partha Biswas, Nobendu Mukerjee, Dhrubo Ahmed Khan, Md Nazmul Hasan, Nazneen Ahmeda Sultana, Md Eram Hosen, Yousef A Bin Jardan, Hiba-Allah Nafidi and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Natural flavonoid isoorientin and its anticancer mechanisms: a systematic review.Naunyn-Schmiedeberg's archives of pharmacology · 2026
    Pooled it
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  12. Profiling of secondary metabolite and evaluation of anti-diabetic potency ofSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 6 countries.

Shopnil AkashFaculty of Allied Health Science, Department of Pharmacy, Daffodil International University, Dhaka, Bangladesh.
Shabana BibiDepartment of Biosciences, Shifa Tameer-e-Millat University, Islamabad, Pakistan.
Partha BiswasLaboratory of Pharmaceutical Biotechnology and Bioinformatics, Department of Genetic Engineering and Biotechnology, Jashore University of Science and Technology, Jashore, Bangladesh.
Nobendu MukerjeeDepartment of Microbiology, West Bengal State University, Kolkata, India.
Dhrubo Ahmed KhanLaboratory of Pharmaceutical Biotechnology and Bioinformatics, Department of Genetic Engineering and Biotechnology, Jashore University of Science and Technology, Jashore, Bangladesh.
Md Nazmul HasanLaboratory of Pharmaceutical Biotechnology and Bioinformatics, Department of Genetic Engineering and Biotechnology, Jashore University of Science and Technology, Jashore, Bangladesh.
Nazneen Ahmeda SultanaFaculty of Allied Health Science, Department of Pharmacy, Daffodil International University, Dhaka, Bangladesh.
Md Eram HosenProfessor Joarder DNA and Chromosome Research Laboratory, Department of Genetic Engineering and Biotechnology, University of Rajshahi, Rajshahi, Bangladesh.
Yousef A Bin JardanDepartment of Food Science, Faculty of Agricultural and Food Sciences, Laval University, Quebec City, QC, Canada.
Hiba-Allah NafidiDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Mohammed BourhiaLaboratory of Chemistry and Biochemistry, Faculty of Medicine and Pharmacy, Ibn Zohr University, Laayoune, Morocco.
Daffodil International University · BDKing Saud University · SAShifa Tameer-e-Millat University · PKUniversité Ibn Zohr · MAUniversité Laval · CAUniversity of Rajshahi · BDWest Bengal State University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast and lung cancer are two of the most lethal forms of cancer, responsible for a disproportionately high number of deaths worldwide. Both doctors and cancer patients express alarm about the rising incidence of the disease globally. Although targeted treatment has achieved enormous advancements, it is not without its drawbacks. Numerous medicines and chemotherapeutic drugs have been authorized by the FDA; nevertheless, they can be quite costly and often fall short of completely curing the condition. Therefore, this investigation has been conducted to identify a potential medication against breast and lung cancer through structural modification of genistein. Genistein is the active compound in

Indexed as

breast cancerdrug designgenisteinGlycyrrhiza glabralung cancermolecular dockingmolecular dynamics simulation

Identifiers

PMID37817764
PMCPMC10561655
OpenAlexW4387056047

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.