Evidence map›Paper›PMID 37817248›Full record

ArticleBMC research notes2023

Genomic, transcriptomic and epigenomic sequencing data of the B-cell leukemia cell line REH.

Mariya Lysenkova Wiklander, Elin Övernäs, Johanna Lagensjö, Amanda Raine, Anna Petri, Ann-Christin Wiman, Jon Ramsell, Yanara Marincevic-Zuniga, Henrik Gezelius, Tom Martin and 11 more

Abstract read
In one paragraph

Article in BMC research notes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Mariya Lysenkova WiklanderDepartment of Medical Sciences and Science for Life Laboratory, Uppsala University, Box 1432, Uppsala, SE-751 44, Sweden.
Elin ÖvernäsDepartment of Medical Sciences and Science for Life Laboratory, Uppsala University, Box 1432, Uppsala, SE-751 44, Sweden.
Johanna LagensjöDepartment of Medical Sciences and Science for Life Laboratory, Uppsala University, Box 1432, Uppsala, SE-751 44, Sweden.
Amanda RaineDepartment of Medical Sciences and Science for Life Laboratory, Uppsala University, Box 1432, Uppsala, SE-751 44, Sweden.
Anna PetriDepartment of Immunology, Genetics and Pathology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Ann-Christin WimanDepartment of Medical Sciences and Science for Life Laboratory, Uppsala University, Box 1432, Uppsala, SE-751 44, Sweden.
Jon RamsellDepartment of Medical Sciences and Science for Life Laboratory, Uppsala University, Box 1432, Uppsala, SE-751 44, Sweden.
Yanara Marincevic-ZunigaDepartment of Medical Sciences and Science for Life Laboratory, Uppsala University, Box 1432, Uppsala, SE-751 44, Sweden.
Henrik GezeliusDepartment of Medical Sciences and Science for Life Laboratory, Uppsala University, Box 1432, Uppsala, SE-751 44, Sweden.
Tom MartinDepartment of Medical Sciences and Science for Life Laboratory, Uppsala University, Box 1432, Uppsala, SE-751 44, Sweden.
Ignas BunikisDepartment of Immunology, Genetics and Pathology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Sara EkbergDepartment of Medical Sciences and Science for Life Laboratory, Uppsala University, Box 1432, Uppsala, SE-751 44, Sweden.
Rikard ErlandssonDepartment of Medical Sciences and Science for Life Laboratory, Uppsala University, Box 1432, Uppsala, SE-751 44, Sweden.
Pontus LarssonDepartment of Medical Sciences and Science for Life Laboratory, Uppsala University, Box 1432, Uppsala, SE-751 44, Sweden.
Mai-Britt MosbechDepartment of Immunology, Genetics and Pathology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Susana HäggqvistDepartment of Immunology, Genetics and Pathology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Susanne Hellstedt KerjeDepartment of Immunology, Genetics and Pathology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Lars FeukDepartment of Immunology, Genetics and Pathology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Adam AmeurDepartment of Immunology, Genetics and Pathology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Ulrika LiljedahlDepartment of Medical Sciences and Science for Life Laboratory, Uppsala University, Box 1432, Uppsala, SE-751 44, Sweden.
Jessica NordlundDepartment of Medical Sciences and Science for Life Laboratory, Uppsala University, Box 1432, Uppsala, SE-751 44, Sweden. jessica.nordlund@medsci.uu.se.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this data paper is to describe a collection of 33 genomic, transcriptomic and epigenomic sequencing datasets of the B-cell acute lymphoblastic leukemia (ALL) cell line REH. REH is one of the most frequently used cell lines for functional studies of pediatric ALL, and these data provide a multi-faceted characterization of its molecular features. The datasets described herein, generated with short- and long-read sequencing technologies, can both provide insights into the complex aberrant karyotype of REH, and be used as reference datasets for sequencing data quality assessment or for methods development. DATA DESCRIPTION: This paper describes 33 datasets corresponding to 867 gigabases of raw sequencing data generated from the REH cell line. These datasets include five different approaches for whole genome sequencing (WGS) on four sequencing platforms, two RNA sequencing (RNA-seq) techniques on two different sequencing platforms, DNA methylation sequencing, and single-cell ATAC-sequencing.

Indexed as

Leukemia, B-CellLeukemia, Lymphocytic, Chronic, B-CellCell LineCell Line, TumorChildEpigenomicsGenomicsHumansTranscriptomeB-ALLCell lineDigital karyotypeEpigenomicsGenomicsLong-readMulti-omicsNext-generation sequencingShort-readTranscriptomics

Identifiers

PMID37817248
PMCPMC10566058

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.