ArticleAntimicrobial resistance and infection control2023
Antibiotic use at a tertiary hospital in Tanzania: findings from a point prevalence survey.
Article in Antimicrobial resistance and infection control, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Prevalence of antimicrobial resistance in Tanzania: A systematic review and meta-analysis.PloS one · 2026Pooled it
- Surveillance of antimicrobial utilization in Africa: a systematic review and meta-analysis of prescription rates, indications, and quality of use from point prevalence surveys.Antimicrobial resistance and infection control · 2024Pooled it
- Point prevalence of evidence-based antimicrobial use among hospitalized patients in sub-Saharan Africa: a systematic review and meta-analysis.Scientific reports · 2024Pooled it
- An explorative approach of the InovSafeCare model for education in infection prevention and control: a cross-sectional study among undergraduate nursing students in sub-Saharan Africa.Global health action · 2026Article
- Pediatric empiric antibiotic use and resistance patterns at a single tertiary care hospital in Tanzania.BMC pediatrics · 2026Article
- A multicenter point-prevalence survey of antibiotic utilization patterns in Ethiopia: implications for strengthening stewardship programs.BMC infectious diseases · 2026Article
- A point prevalence survey on antibiotic dispensing practices identifies targets for quality improvement of antimicrobial stewardship in community pharmacies in Dar es Salaam, Tanzania.Journal of pharmaceutical policy and practice · 2026Article
- Drivers influencing antibiotics use in pediatric wards across five public hospitals in Zanzibar: a WHO multiple point prevalence survey.Frontiers in antibiotics · 2026Article
- Barriers and facilitators for the implementation of Antimicrobial Stewardship Programs in Dar es Salaam Regional Referral Hospitals (RRHs).PLOS global public health · 2026Article
- Prevalence and patterns of antibiotic prescriptions in Conakry hospitals, Guinea: a multicentre cross-sectional survey.JAC-antimicrobial resistance · 2025Article
- Antimicrobial Use at a Tertiary-Care Hospital in Türkiye According to the WHO Access, Watch and Reserve (AWaRe) Classification: A Point Prevalence Survey.Infectious diseases & clinical microbiology · 2025Article
- Current status and future direction of antimicrobial stewardship programs and antibiotic prescribing in primary care hospitals in Zambia.JAC-antimicrobial resistance · 2025Article
- Surgical prophylaxis in Haydom Lutheran Hospital, Tanzania - learning from a point prevalence survey.Infection prevention in practice · 2025Article
- Antibiotic use at the Centre Hospitalier Universitaire de Zone d'Abomey Calavi/Sô-Ava (CHUZ/AS) in Benin: a point prevalence survey.JAC-antimicrobial resistance · 2025Article
- PHENOTYPIC ANTIBIOTIC RESISTANCE PROFILES OF GRAM-NEGATIVE BACTERIA IN CLINICAL SAMPLES PRE AND DURING COVID-19 PANDEMIC AT ZONAL REFERRAL HOSPITAL NORTHERN TANZANIA.African journal of infectious diseases · 2025Article
- High Prevalence of Antimicrobial Prescribing Among Public Health Facilities in Central Uganda: Findings from Point Prevalence Survey.Infection and drug resistance · 2025Article
- Point prevalence survey of antibiotics in a pediatric tertiary hospital in the Republic of Panama.Revista panamericana de salud publica = Pan American journal of public health · 2025Article
- Antibiotic use and adherence to the WHO AWaRe guidelines across 16 hospitals in Zambia: a point prevalence survey.JAC-antimicrobial resistance · 2024Article
- Surveillance of antibiotics use in inpatients at Benjamin Mkapa Zonal Referral Hospital in Dodoma, Tanzania: a point prevalence survey.BMJ open · 2024Article
- Assessment of antimicrobial stewardship programmes and antibiotic use among children admitted to two hospitals in Sierra Leone: a cross-sectional study.Antimicrobial resistance and infection control · 2024Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn Tanzania, data on antibiotic use at the patient level is scarce, and intervention measures to optimize antibiotic use and reduce antimicrobial resistance are rarely performed.
objectivesTo describe antibiotic use at Muhimbili National Hospital.
methodsThis was a point prevalence survey on antibiotic use conducted at Muhimbili National Hospital in August-September 2022. The World Health Organization point prevalence survey data collection tool was used to collect patients' information from the files. All patients admitted to the wards on the day of the survey were included.
resultsOverall, 47% (185/397) of admitted patients were on at least one antibiotic during the survey. All antibiotics prescribed were for empirical treatment and guideline compliance was low, at 45%. Of 185 patients who received antibiotics, the most common indication was community acquired infection (55%) and 36% had no documentation of the reasons for prescribing antibiotics. Almost 75% of the antibiotics were administered parenterally, with only 2% switching to oral route. Microbiological tests were performed in only 9 (5%) patients out of 185 and results were available for only one patient. Of all participants, 52% received two or more antibiotic in combination, with the combination ceftriaxone-metronidazole being most frequently prescribed, followed by the combination of ampicillin, cloxacillin, and gentamicin. For individual antibiotics, ceftriaxone was the most frequently prescribed antibiotic accounting for 28% (79/283), followed by metronidazole (24%) and amoxicillin-clavulanic acid (11%).
conclusionThe findings of a high prevalence of antibiotic use, inadequate use of bacterial culture, and frequent empiric antibiotic treatment suggests the need for strengthening diagnostic and antimicrobial stewardship programs. Furthermore, this study has identified areas for quality improvement, including education programs focusing on prescription practice.
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