Evidence map›Paper›PMID 37817166›Full record

Observational studyBMC endocrine disorders2023

High number of hypoglycaemic episodes identified by CGM among home-dwelling older people with diabetes: an observational study in Norway.

Mari Fløde, Monica Hermann, Anne Haugstvedt, Eirik Søfteland, Jannicke Igland, Anders Åsberg, Trond Geir Jenssen, Marit Graue

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC endocrine disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Review
  9. Individualized treatment of diabetes mellitus in older adults.Geriatrics & gerontology international · 2024
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Mari FlødeDepartment of Health and Caring Sciences, Western Norway University of Applied Sciences, Bergen, Norway.
Monica HermannDepartment of Health and Caring Sciences, Western Norway University of Applied Sciences, Bergen, Norway.
Anne HaugstvedtDepartment of Health and Caring Sciences, Western Norway University of Applied Sciences, Bergen, Norway.
Eirik SøftelandDepartment of Medicine, Haukeland University Hospital, Bergen, Norway.
Jannicke IglandDepartment of Health and Caring Sciences, Western Norway University of Applied Sciences, Bergen, Norway.
Anders ÅsbergDepartment of Transplantation Medicine, Oslo University Hospital, Oslo, Norway.
Trond Geir JenssenDepartment of Transplantation Medicine, Oslo University Hospital, Oslo, Norway.
Marit GraueDepartment of Health and Caring Sciences, Western Norway University of Applied Sciences, Bergen, Norway. marf@hvl.no.
Western Norway University of Applied Sciences · NOUniversity of Bergen · NOOslo University Hospital · NOUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA scoping review from 2021 identified a lack of studies on the incidence, prevention and management of hypoglycaemia in home-dwelling older people with diabetes. The aim of this study was to investigate the frequency and duration of hypoglycaemic episodes measured by continuous glucose monitoring (CGM) in older people with diabetes who received home care and who were treated with glucose-lowering medications, and to compare the frequency and duration of hypoglycaemic episodes between subgroups of the study population according to demographic and clinical variables.

methodsThis was an observational study investigating the occurrence of hypoglycaemia in people with diabetes aged ≥ 65 years. Data were collected using blinded continuous glucose monitoring (CGM, iPro2) for 5 consecutive days. Frequency and duration of hypoglycaemic episodes were assessed using a sensor glucose cut-off value of 3.9 mmol/L. A blood sample for measurement of HbA1c and creatinine-based eGFR (CKD-EPI) was obtained during the monitoring period. Demographic and clinical data were collected from electronic patient records.

resultsFifty-six individuals were enrolled (median age 82 years and 52% were men). Of the 36 participants who were treated with insulin, 33% had at least one hypoglycaemic episode during the five-day period. Among 18 participants who neither used insulin nor sulfonylurea, but other glucose-lowering medications, 44% had at least one hypoglycaemicepisode. Of those with hypoglycaemic episodes, 86% lived alone. The median duration of the hypoglycaemia was 1 h and 25 min, ranging from 15 min to 8 h and 50 min.

conclusionThis study identified an unacceptably high number of unknown hypoglycaemic episodes among older home-dwelling people with diabetes receiving home care, even among those not using insulin or sulfonylurea. The study provides essential knowledge that can serve as a foundation to improve the treatment and care for this vulnerable patient group. The routines for glucose monitoring and other prevention tasks need to be considered more comprehensively, also, among those treated with glucose-lowering medications other than insulin.

Indexed as

Diabetes Mellitus, Type 1HypoglycemiaAgedAged, 80 and overBlood GlucoseBlood Glucose Self-MonitoringFemaleHumansHypoglycemic AgentsInsulinMaleSulfonylurea CompoundsBlood GlucoseHypoglycemic AgentsInsulinSulfonylurea CompoundsClinical pharmacologyDiabetesDrug safetyHome careHypoglycaemiaOlder people

Identifiers

PMID37817166
PMCPMC10566065
OpenAlexW4387496085

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.