Evidence map›Paper›PMID 37817129›Full record

ArticleBMC public health2023

Awareness, attitudes towards genetic diseases and acceptability of genetic interventions among pregnant women in Burera district, Rwanda.

Jean Baptiste Niyibizi, Erigene Rutayisire, Monica Mochama, Michael Habtu, Zephanie Nzeyimana, Daniel Seifu

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Jean Baptiste NiyibiziSchool of Public Health, Mount Kenya University, Kigali Campus, Rwanda. niyibizi3@gmail.com.
Erigene RutayisireSchool of Public Health, University of Rwanda, Kigali, Rwanda.
Monica MochamaSchool of Public Health, Mount Kenya University, Kigali Campus, Rwanda.
Michael HabtuSchool of Public Health, University of Rwanda, Kigali, Rwanda.
Zephanie NzeyimanaICAP Global Health, Columbia University, Kigali, Rwanda.
Daniel SeifuSchool of Medicine, Basic Medical Sciences Division, University of Global Health Equity (UGHE), Butaro, Rwanda.
University of Global Health Equity · RWUniversity of Kigali · RWMount Kenya University · KE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Approximately 3% of all pregnancies are associated with conditions linked with disability, either mild or severe congenital diseases. This is a consequence of environmental and genetic exposures. Complications and poor management of these diseases arise due to limited knowledge, awareness about the disease, and limited resource settings. The current study assessed awareness, attitudes towards genetic diseases, and acceptability of genetic interventions among pregnant women. This was a cross-sectional study that was conducted among 664 pregnant women in six selected health centers in Burera district using a detailed questionnaire. The data were analysed using STATA Version 15 and entailed univariate, bivariate, and multivariable analyses. The level of significance was set at p < 0.05. The mean age of the study participants was 28, and most of them were in the age range of 21 to 30 (50%). Most of the participants were married (91.1%), Christians (98.4%), farmers (92.7%), used public health coverage (96.6%), and attained primary studies (66.1%). The findings from this study showed that among participants, adequate awareness was at 29.5%, inadequate awareness at 70.5%, positive attitudes at 87.1%, negative attitudes at 12.9%, high acceptability at 97.1%, and low acceptability at 2.9%. While there was no significant difference between awareness and acceptability, there was a statistical significance between attitudes towards genetic diseases and acceptability towards the use of genetic services (p < 0.01). There was no statistical significance between sociodemographic or obstetric characteristics and the acceptability of genetic interventions. Participants with positive attitudes towards genetic diseases were more likely to develop a high level of acceptability and willingness towards the use of genetic interventions (OR: 5.3 [2.1-13.5]). Improving awareness about genetic diseases and establishing genetic interventions in healthcare facilities are needed.

Indexed as

Persons with DisabilitiesPregnant PeopleCross-Sectional StudiesFemaleHealth Knowledge, Attitudes, PracticeHumansPregnancyRwandaAcceptabilityAttitudeAwarenessGenetic diseasesGenetic interventions

Identifiers

PMID37817129
PMCPMC10563347
OpenAlexW4387501396

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.