Evidence map›Paper›PMID 37816570›Full record

ArticleBMJ open2023

Retinopathy among women with hypertensive disorders of pregnancy attending hospitals in Mbarara city, south-western Uganda: a cross-sectional study.

Ibrahimu Zamaladi, Sam Ruvuma, Carmel M Mceniery, Teddy Kwaga, Ian B Wilkinson, Daniel Atwine, Henry Mark Lugobe

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Ibrahimu ZamaladiDepartment of Ophthalmology, Mbarara University of Science and Technology, Mbarara, Uganda.
Sam RuvumaDepartment of Ophthalmology, Mbarara University of Science and Technology, Mbarara, Uganda.
Carmel M McenieryDivision of Experimental Medicine and Immunotherapeutics, Department of Medicine, University of Cambridge, Cambridge, UK.
Teddy KwagaDepartment of Ophthalmology, Mbarara University of Science and Technology, Mbarara, Uganda.
Ian B WilkinsonDivision of Experimental Medicine and Immunotherapeutics, Department of Medicine, University of Cambridge, Cambridge, UK.
Daniel AtwineDepartment of Clinical Research, Soar Research Foundation, Mbarara, Uganda.
Henry Mark LugobeDivision of Experimental Medicine and Immunotherapeutics, Department of Medicine, University of Cambridge, Cambridge, UK henrylugobe@must.ac.ug.ORCID 0000-0001-8177-8786
Mbarara University of Science and Technology · UGUniversity of Cambridge · GB

Funding

Training in noncommunicable diseases epidemiological, data science and Implementation Science research to strengthen evidence-based interventions, policy and control in Uganda.D43TW011401 · FIC · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI Charles Batte, William Checkley · 2019 to 2026
$1.8M
FIC NIH HHS D43 TW011401
6 · The paper itself

Abstract

objectiveRetinopathy is one of the complications occurring among women with hypertensive disorders of pregnancy. We sought to determine the prevalence and factors associated with retinopathy among women with hypertensive disorders of pregnancy in southwestern Uganda.

designThis was a hospital-based cross-sectional study from November 2019 to March 2020.

settingThree selected hospitals in Mbarara city, south-western Uganda.

participantsThe study included all pregnant women with hypertensive disorders of pregnancy. PRIMARY AND SECONDARY OUTCOME MEASURES: The participants were screened for retinopathy using a fundus camera. Data on participant's sociodemographics, obstetrics and medical factors were collected. The prevalence of retinopathy was determined and multivariable logistic regression was used to determine the independent factors associated with retinopathy.

resultsA total of 216 women with hypertensive disorders of pregnancy were enrolled in this study. The prevalence of retinopathy was 60.2% (130/216). The most common retinal lesions were grade 1 retinopathy (narrowing of arterioles) accounting for 86.9% (113/130), grade 3 (retinal haemorrhages) was present in 10% (13/130) of women and grade 4 (papilloedema) in 3% (4/130). In an adjusted analysis, severe hypertension was significantly associated with retinopathy (aOR=2.8; 95% CI: 1.36 to 5.68). Grandmultigravida women were also associated with retinopathy (aOR=2.4; 95% CI: 0.99 to 5.72) with a tendency towards significancy, p=0.051.

conclusionsIn our study, retinopathy was common among women with hypertensive disorders of pregnancy. Women presenting with severe hypertension were likely to have retinopathy. There is a need to integrate screening for retinopathy in the care cascade of women with hypertensive disorders of pregnancy.

Indexed as

Hypertension, Pregnancy-InducedRetinal DiseasesCross-Sectional StudiesFemaleHospitalsHumansPregnancyPrevalenceUgandaHypertensionMaternal medicineMedical ophthalmology

Identifiers

PMID37816570
PMCPMC10565131
OpenAlexW4387503941

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.