Evidence map›Paper›PMID 37816537›Full record

ArticleBMJ global health2023

Association between the extension of smoke-free legislation and incident acute myocardial infarctions in Singapore from 2010 to 2019: an interrupted time-series analysis.

Jamie S Y Ho, Andrew F W Ho, Eric Jou, Nan Liu, Huili Zheng, Joel Aik

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Article in BMJ global health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jamie S Y HoDepartment of Medicine, National University Hospital, National University Health System, Singapore.
Andrew F W HoProgramme in Health Services and Systems Research, Duke-NUS Medical School, Singapore.
Eric JouQueens' College, University of Cambridge, Cambridge, UK.
Nan LiuProgramme in Health Services and Systems Research, Duke-NUS Medical School, Singapore.
Huili ZhengNational Registry of Diseases Office, Health Promotion Board, Singapore.
Joel AikProgramme in Health Services and Systems Research, Duke-NUS Medical School, Singapore joelaik@duke-nus.edu.sg joelaik@hotmail.com.ORCID 0000-0002-2851-9424

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe examined the association between smoke-free laws implemented in the outdoors and the common areas of residential apartment blocks and reported acute myocardial infarctions (AMI) in Singapore.

methodsWe used an interrupted time-series design and seasonal autoregressive integrated moving average models to examine the effect of the smoke-free law extensions in 2013 (common areas of residential blocks, covered pedestrian linkways, overhead bridges and within 5 m of bus stops), 2016 (parks) and 2017 (educational institutions, buses and taxis) on the monthly incidence rate of AMIs per 1 000 000 population.

resultsWe included 133 868 AMI reports from January 2010 to December 2019. Post-2013, there was a decrease in the AMI incidence trend (β=-0.6 per month, 95%CI -1.0 to -0.29) and 2097 (95% CI 2094 to 2100) more AMIs may have occurred without the extension. There was a significant step-decline in male AMIs and a non-significant step-increase in female AMIs post-2013. Those 65 years and older experienced a greater decline to the postlegislation 2013 trend (β=-5.9, 95% CI -8.7 to -3.1) compared with those younger (β=-0.4, 95% CI -0.6 to -0.2), while an estimated 19 591 (15 711 to 23472) additional AMI cases in those 65 years and above may have occurred without the extension. We found a step-increase in monthly AMI incidence post-2016 (β=14.2, 95%CI 3.3 to 25.0).

conclusionThe 2013 smoke-free law extension to residential estates and other outdoor areas were associated with a decline in AMIs and those above the age of 65 years and men appeared to be major beneficiaries. Additional epidemiological evidence is required to support the expanded smoke-free legislation to parks, educational institutions, buses and taxis.

Indexed as

Myocardial InfarctionAgedFemaleHumansIncidenceInterrupted Time Series AnalysisMaleSingaporecardiovascular diseaseenvironmental healthepidemiologyhealth policypublic health

Identifiers

PMID37816537
PMCPMC10565237

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