Trial reportJCO oncology practice2023
Axillary Treatment and Chronic Breast Cancer-Related Lymphedema: Implications for Prospective Surveillance and Intervention From a Randomized Controlled Trial.
Trial report in JCO oncology practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 15 citations in OpenAlex.
- Trial
- The Importance of a Pre-treatment Baseline When Screening Patients for Breast-Cancer-Related Lymphedema.Annals of surgical oncology · 2025Trial
- Timing of Breast Cancer Related Lymphedema Development Over 3 Years: Observations from a Large, Prospective Randomized Screening Trial Comparing Bioimpedance Spectroscopy (BIS) Versus Tape Measure.Annals of surgical oncology · 2024Trial
- Lymphatic pumping failure in the arm precedes dermal backflow and breast cancer-related lymphedema.Breast cancer research : BCR · 2026Article
- Effectiveness of telehealth versus face-to-face appointments in identifying complications following breast cancer surgery.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Advancing Lymphedema Surveillance With Evidence-Based Practices.Clinical journal of oncology nursing · 2025Review
- Enhancing Quality of Life: The Effect of Complete Decongestive Therapy on Jordanian Women With Breast Cancer After Axillary Lymph Node Dissection.European journal of breast health · 2025Article
- Bibliometric and visual analysis of breast cancer-related lymphedema: Knowledge structure, research status, and future trends.Medicine · 2025Article
- Evidence-based recommendations regarding risk reduction practices for people at risk of or with breast cancer-related lymphedema: consensus from an expert panel.Medical oncology (Northwood, London, England) · 2024Article
- Biomarkers in lymphedema assessment: integrating elastography and muti-frequency bioimpedance analysis.Biomarkers in medicine · 2024Article
Corrections and comments
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Authors and funding
7 authors at 7 institutions in 2 countries.
Funding
Abstract
purposeThe PREVENT randomized trial assessed progression to chronic breast cancer-related lymphedema (cBCRL) after intervention triggered by bioimpedance spectroscopy (BIS) or tape measurement (TM). This secondary analysis identifies cBCRL risk factors on the basis of axillary treatment.
methodsBetween June 2014 and September 2018, 881 patients received sentinel node biopsy (SNB; n = 651), SNB + regional node irradiation (RNI; n = 58), axillary lymph node dissection (ALND; n = 85), or ALND + RNI (n = 87). The primary outcome was the 3-year cBCRL rate requiring complex decongestive physiotherapy (CDP).
resultsAfter a median follow-up of 32.8 months (IQR, 21-34.3), 69 of 881 patients (7.8%) developed cBCRL. For TM, 43 of 438 (9.8%) developed cBCRL versus 26 of 443 (5.9%) for BIS (
conclusionThe extent of axillary treatment is a significant risk factor for cBCRL. Increasing BMI, rurality, SCF radiation, and taxane chemotherapy also increase risk. These results have implications for a proposed risk-based lymphedema screening, early intervention, and treatment program.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.