Evidence map›Paper›PMID 37816068›Full record

ArticleACS applied materials & interfaces2023

Potentiating the Immune Responses of HBsAg-VLP Vaccine Using a Polyphosphoester-Based Cationic Polymer Adjuvant.

Xuhan Liu, Yifan Liu, Xiaoyu Yang, Xinyu Lu, Xiao-Ning Xu, Jiancheng Zhang, Rongjun Chen

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied materials & interfaces, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Xuhan LiuDepartment of Chemical Engineering, Imperial College London, South Kensington Campus, London SW7 2AZ, U.K.
Yifan LiuDepartment of Chemical Engineering, Imperial College London, South Kensington Campus, London SW7 2AZ, U.K.
Xiaoyu YangAIM Honesty Biopharmaceutical Co., Ltd, Dalian 116620, China.
Xinyu LuDepartment of Chemical Engineering, Imperial College London, South Kensington Campus, London SW7 2AZ, U.K.
Xiao-Ning XuDepartment of Infectious Diseases, Imperial College London, London W12 0NN, U.K.
Jiancheng ZhangAIM Honesty Biopharmaceutical Co., Ltd, Dalian 116620, China.
Rongjun ChenDepartment of Chemical Engineering, Imperial College London, South Kensington Campus, London SW7 2AZ, U.K.ORCID 0000-0002-8133-5472
Imperial College London · GBShenzhen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Virus-like particle (VLP)-based vaccines are required to be associated with a suitable adjuvant to potentiate their immune responses. Herein, we report a novel, biodegradable, and biocompatible polyphosphoester-based amphiphilic cationic polymer, poly(ethylene glycol)-

Indexed as

Hepatitis B Surface AntigensVaccines, Virus-Like ParticleAdjuvants, ImmunologicAdjuvants, PharmaceuticAdjuvants, VaccineAnimalsHepatitis B VaccinesImmunity, CellularMiceMice, Inbred BALB CPolymersAdjuvants, ImmunologicAdjuvants, PharmaceuticAdjuvants, VaccineHepatitis B Surface AntigensHepatitis B VaccinesPolymersVaccines, Virus-Like Particleadjuvantcationic polymerHBV vaccineimmune responsepolyphosphoestervirus-like particle

Identifiers

PMID37816068
PMCPMC10614196
OpenAlexW4387492900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.