Evidence map›Paper›PMID 37815731›Full record

ArticleHernia : the journal of hernias and abdominal wall surgery2024

STRONGHOLD first-year results of biomechanically calculated abdominal wall repair: a propensity score matching.

C Lesch, R Nessel, D Adolf, M Hukauf, F Köckerling, F Kallinowski, STRONGHOLD/Herniamed-Collaborators GROUP, A Willms, R Schwab, K Zarras

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In one paragraph

Article in Hernia : the journal of hernias and abdominal wall surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

C LeschGeneral, Visceral and Transplantation Surgery, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany. carolin.lesch@stud.uni-heidelberg.de.ORCID 0000-0001-9062-7728
R NesselGeneral, Visceral and Pediatric Surgery, Klinikum Am Gesundbrunnen, Am Gesundbrunnen 20‑26, 74078, Heilbronn, Germany.
D AdolfStatConsult, Am Fuchsberg 11, 39112, Magdeburg, Germany.
M HukaufStatConsult, Am Fuchsberg 11, 39112, Magdeburg, Germany.
F KöckerlingVivantes Humboldt Hospital Berlin, Center for Hernia Surgery, Academic Teaching Hospital of Charité University Medicine, Am Nordgraben 2, 13509, Berlin, Germany.
F KallinowskiGeneral, Visceral and Transplantation Surgery, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
STRONGHOLD/Herniamed-Collaborators GROUP
A WillmsGeneral and Visceral Surgery, Bundeswehrkrankenhaus Hamburg, Lesserstrasse 180, 22049, Hamburg, Germany.
R SchwabGeneral, Visceral and Thorax Surgery, BundeswehrZentralkrankenhaus Koblenz, Rübenacher Strasse 170, 56072, Koblenz, Germany.
K ZarrasVisceral, Minimal Invasive and Oncological Surgery, Marien Hospital Düsseldorf, Schloßstraße 85, 40477, Düsseldorf, Germany.
Bundeswehrkrankenhaus · DEHeidelberg University · DEInfoConsult (Germany) · DEMarien Hospital Düsseldorf · DESLK-Kliniken Heilbronn · DEVivantes Klinikum · DE

Funding

Heidelberger Stiftung Chirurgie 2016/22Heidelberger Stiftung Chirurgie 2017/171Heidelberger Stiftung Chirurgie 2018/215Heidelberger Stiftung Chirurgie 2019/288Heidelberger Stiftung Chirurgie 2020/376 und 2021/444
6 · The paper itself

Abstract

purposeEvery year around 70,000 people in Germany suffer from an abdominal incisional hernia that requires surgical treatment. Five years after reconstruction about 25% reoccur. Incisional hernias are usually closed with mesh using various reconstruction techniques, summarized here as standard reconstruction (SR). To improve hernia repair, we established a concept for biomechanically calculated reconstructions (BCR). In the BCR, two formulas enable customized patient care through standardized biomechanical measures. This study aims to compare the clinical outcomes of SR and BCR of incisional hernias after 1 year of follow-up based on the Herniamed registry.

methodsSR includes open retromuscular mesh augmented incisional hernia repair according to clinical guidelines. BCR determines the required strength (Critical Resistance to Impacts related to Pressure = CRIP) preoperatively depending on the hernia size. It supports the surgeon in reliably determining the Gained Resistance, based on the mesh-defect-area-ratio, further mesh and suture factors, and the tissue stability. To compare SR and BCR repair outcomes in incisional hernias at 1 year, propensity score matching was performed on 15 variables. Included were 301 patients with BCR surgery and 23,220 with standard repair.

resultsBCR surgeries show a significant reduction in recurrences (1.7% vs. 5.2%, p = 0.0041), pain requiring treatment (4.1% vs. 12.0%, p = 0.001), and pain at rest (6.9% vs. 12.7%, p = 0.033) when comparing matched pairs. Complication rates, complication-related reoperations, and stress-related pain showed no systematic difference.

conclusionBiomechanically calculated repairs improve patient care. BCR shows a significant reduction in recurrence rates, pain at rest, and pain requiring treatment at 1-year follow-up compared to SR.

Indexed as

Abdominal WallHernia, VentralIncisional HerniaHerniorrhaphyHumansPainPropensity ScoreAbdominal wall reconstructionBiomechanically calculated incisional hernia repairHerniamedIncisional herniaPropensity score matching for incisional hernia repairSTRONGHOLD

Identifiers

PMID37815731
PMCPMC10891228
OpenAlexW4387472278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.