Evidence map›Paper›PMID 37815447›Full record

ReviewRadiology2023

Expanding Role of Advanced Image Analysis in CT-detected Indeterminate Pulmonary Nodules and Early Lung Cancer Characterization.

Ashley Elizabeth Prosper, Michael N Kammer, Fabien Maldonado, Denise R Aberle, William Hsu

Open access · greenAbstract readReview
In one paragraph

Review in Radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ashley Elizabeth ProsperFrom the Department of Radiological Sciences, David Geffen School of Medicine at UCLA, 924 Westwood Blvd, Suite 420, Los Angeles, CA 90024 (A.E.P., D.R.A., W.H.); Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn (M.N.K., F.M.); and Department of Bioengineering, UCLA Samueli School of Engineering, Los Angeles, Calif (D.R.A., W.H.).ORCID 0000-0001-8615-5246
Michael N KammerFrom the Department of Radiological Sciences, David Geffen School of Medicine at UCLA, 924 Westwood Blvd, Suite 420, Los Angeles, CA 90024 (A.E.P., D.R.A., W.H.); Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn (M.N.K., F.M.); and Department of Bioengineering, UCLA Samueli School of Engineering, Los Angeles, Calif (D.R.A., W.H.).
Fabien MaldonadoFrom the Department of Radiological Sciences, David Geffen School of Medicine at UCLA, 924 Westwood Blvd, Suite 420, Los Angeles, CA 90024 (A.E.P., D.R.A., W.H.); Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn (M.N.K., F.M.); and Department of Bioengineering, UCLA Samueli School of Engineering, Los Angeles, Calif (D.R.A., W.H.).ORCID 0000-0002-6504-2063
Denise R AberleFrom the Department of Radiological Sciences, David Geffen School of Medicine at UCLA, 924 Westwood Blvd, Suite 420, Los Angeles, CA 90024 (A.E.P., D.R.A., W.H.); Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn (M.N.K., F.M.); and Department of Bioengineering, UCLA Samueli School of Engineering, Los Angeles, Calif (D.R.A., W.H.).ORCID 0000-0002-8858-3401
William HsuFrom the Department of Radiological Sciences, David Geffen School of Medicine at UCLA, 924 Westwood Blvd, Suite 420, Los Angeles, CA 90024 (A.E.P., D.R.A., W.H.); Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn (M.N.K., F.M.); and Department of Bioengineering, UCLA Samueli School of Engineering, Los Angeles, Calif (D.R.A., W.H.).ORCID 0000-0002-5168-070X
UCLA Medical Center · US

Funding

The Boston University - UCLA Lung Cancer Biomarker Characterization CenterU2CCA271898 · NCI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Jennifer Ellen Beane, Steven M. Dubinett · 2022 to 2026
$5.5M
Novel Integrative Approach for the Early Detection of Lung Cancer using Repeated MeasuresR01CA253923 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI LANDMAN, BENNETT A., MALDONADO, FABIEN · 2021 to 2025
$3.4M
Computational Toolkit for Normalizing the Impact of CT Acquisition and Reconstruction on Quantitative Image FeaturesR01EB031993 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HSU, WILLIAM, MCNITT-GRAY, MICHAEL F · 2022 to 2024
$2.1M
NCI NIH HHS R01 CA253923NCI NIH HHS U2C CA271898NIBIB NIH HHS R01 EB031993
6 · The paper itself

Abstract

The implementation of low-dose chest CT for lung screening presents a crucial opportunity to advance lung cancer care through early detection and interception. In addition, millions of pulmonary nodules are incidentally detected annually in the United States, increasing the opportunity for early lung cancer diagnosis. Yet, realization of the full potential of these opportunities is dependent on the ability to accurately analyze image data for purposes of nodule classification and early lung cancer characterization. This review presents an overview of traditional image analysis approaches in chest CT using semantic characterization as well as more recent advances in the technology and application of machine learning models using CT-derived radiomic features and deep learning architectures to characterize lung nodules and early cancers. Methodological challenges currently faced in translating these decision aids to clinical practice, as well as the technical obstacles of heterogeneous imaging parameters, optimal feature selection, choice of model, and the need for well-annotated image data sets for the purposes of training and validation, will be reviewed, with a view toward the ultimate incorporation of these potentially powerful decision aids into routine clinical practice.

Indexed as

Lung NeoplasmsMultiple Pulmonary NodulesHumansImage Processing, Computer-AssistedTomography, X-Ray Computed

Identifiers

PMID37815447
PMCPMC10623199
OpenAlexW4387473362

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.