Evidence map›Paper›PMID 37815382›Full record

ArticleCurrent eye research2024

A Comparison of Culture Results and Visual Acuity in Contact Lens Related Microbial Keratitis.

Jenna N Hart, Ming-Chen Lu, Breanna M Tracey, Keith D Miller, Paul R Lephart, Shahzad I Mian, Maria A Woodward

Abstract read
In one paragraph

Article in Current eye research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jenna N HartDepartment of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI, USA.
Ming-Chen LuDepartment of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI, USA.
Breanna M TraceyDepartment of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI, USA.
Keith D MillerDepartment of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI, USA.
Paul R LephartDepartment of Pathology, University of Michigan, Ann Arbor, MI, USA.
Shahzad I MianDepartment of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI, USA.
Maria A WoodwardDepartment of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0001-7060-9004

Funding

VIVARIUM MODULEP30EY007003 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI David Antonetti · 1987 to 2026
$17.6M
Quantifying Microbial Keratitis to Predict Outcomes: An Imaging and Epidemiologic ApproachR01EY031033 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WOODWARD, MARIA ANNEKE · 2020 to 2023
$1.8M
NEI NIH HHS P30 EY007003NEI NIH HHS R01 EY031033
6 · The paper itself

Abstract

purposeEvaluate the effect of corneal and contact lens-related (CLR) culture results on visual acuity (VA) in patients with microbial keratitis (MK).

methodsMK patients with corneal and CLR cultures were identified in the University of Michigan electronic health record from August 2012 to April 2022. Test results were classified as laboratory-positive or laboratory-negative. Linear regression was used to examine trends of VA and associations between changes in VA (differences of VA at 90-day and baseline VA) and corneal and CLR culture results, after adjustment for baseline VA. One-sample t-tests were used to test if the slope estimates were different from zero.

resultsMK patients (

conclusionsPositive CLR cultures are associated with significant improvement in VA over time. These additional cultures can provide guidance on appropriate antimicrobial selection, especially when corneal cultures are negative.

Indexed as

Contact LensesCorneal UlcerEye Infections, BacterialKeratitisFemaleHumansMaleMiddle AgedRetrospective StudiesVisual AcuityContact lenscorneal ulcermicrobial keratitismicrobiologyvisual acuity

Identifiers

PMID37815382
PMCPMC10842689

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.