Evidence map›Paper›PMID 37815316›Full record

ArticleThe Journal of international medical research2023

Effect of mode of delivery on neonatal oxidative stress and dynamic thiol-disulfide homeostasis.

Serife Ozlem Genc, Huseyin Erdal

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Serife Ozlem GencDepartment of Obstetrics and Gynecology, Aksaray University Training and Research Hospital, Aksaray, Turkey.ORCID 0000-0002-9811-2726
Huseyin ErdalDepartment of Medical Genetics, School of Medicine, Aksaray University, Aksaray, Turkey.ORCID 0000-0003-0786-5077
Aksaray University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the effect of the mode of delivery on neonatal oxidative stress and dynamic thiol-disulfide homeostasis.

methodsSixty women who were followed up in the Obstetrics and Gynecology clinic were included in this prospective study. Cord blood samples were obtained from women who underwent cesarean section (CS) and vaginal delivery (VD). Total oxidant status and total antioxidant status levels were measured by spectrophotometry. The dynamic thiol-disulfide balance was determined by colorimetry.

resultsThe total antioxidant status and oxidative stress index levels were higher and total oxidant status levels were lower in the VD group compared with the CS group. Native and total thiol levels were higher while disulfide levels were lower in the VD compared with the CS delivery group, while disulfide levels were higher in the CS group.

conclusionThese results indicate that disulfide formation leads to decreased antioxidant capacity in women undergoing CS. Monitoring of dynamic thiol-disulfide levels may thus provide clinicians with important information on the oxidative stress status in newborns.

Indexed as

AntioxidantsCesarean SectionBiomarkersDisulfidesFemaleHomeostasisHumansInfant, NewbornOxidantsOxidative StressPregnancyProspective StudiesSulfhydryl CompoundsAntioxidantsBiomarkersDisulfidesOxidantsSulfhydryl CompoundsCesarean sectioncord bloodmode of deliverynewbornoxidative stressthiol–disulfide homeostasis

Identifiers

PMID37815316
PMCPMC10566282
OpenAlexW4387472721

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.