Evidence map›Paper›PMID 37815183›Full record

ReviewCurrent drug delivery2024

A Comprehensive Review on Imperative Role of Ionic Liquids in Pharmaceutical Sciences.

Prerna Uniyal, Shibam Das, Surbhi Panwar, Neelima Kukreti, Pankaj Nainwal, Rohit Bhatia

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current drug delivery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Prerna UniyalSchool of Pharmacy, Graphic Era Hill University, Dehradun-248002, India.
Shibam DasDepartment of pharmaceutical technology, Meerut Institute of Engineering and Technology, Meerut, Uttar Pradesh, India.
Surbhi PanwarSchool of Pharmacy, Graphic Era Hill University, Dehradun-248002, India.
Neelima KukretiSchool of Pharmacy, Graphic Era Hill University, Dehradun-248002, India.
Pankaj NainwalSchool of Pharmacy, Graphic Era Hill University, Dehradun-248002, India.
Rohit BhatiaDepartment of Pharmaceutical Chemistry and Analysis, ISF College of Pharmacy, Ghal Kalan, Ferozpur G.T. Road MOGA-142001, Punjab, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ionic liquids (ILs) are poorly-coordinated ionic salts that can exist as a liquid at room temperatures (or <100 °C). ILs are also referred to as "designer solvents" because so many of them have been created to solve particular synthetic issues. ILs are regarded as "green solvents" because they have several distinctive qualities, including better ionic conduction, recyclability, improved solvation ability, low volatility, and thermal stability. These have been at the forefront of the most innovative fields of science and technology during the past few years. ILs may be employed in new drug formulation development and drug design in the field of pharmacy for various functions such as improvement of solubility, targeted drug delivery, stabilizer, permeability enhancer, or improvement of bioavailability in the development of pharmaceutical or vaccine dosage formulations. Ionic liquids have become a key component in various areas such as synthetic and catalytic chemistry, extraction, analytics, biotechnology, etc., due to their superior abilities along with highly modifiable potential. This study concentrates on the usage of ILs in various pharmaceutical applications enlisting their numerous purposes from the delivery of drugs to pharmaceutical synthesis. To better comprehend cuttingedge technologies in IL-based drug delivery systems, highly focused mechanistic studies regarding the synthesis/preparation of ILs and their biocompatibility along with the ecotoxicological and biological effects need to be studied. The use of IL techniques can address key issues regarding pharmaceutical preparations such as lower solubility and bioavailability which plays a key role in the lack of effectiveness of significant commercially available drugs.

Indexed as

Ionic LiquidsChemistry, PharmaceuticalDrug Delivery SystemsHumansPharmaceutical PreparationsSolubilityIonic LiquidsPharmaceutical Preparationsdesigner solventsdrug deliveryILs in formulationsIonic liquidspharmaceutical ILspharmaceutics.

Identifiers

PMID37815183

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.