Evidence map›Paper›PMID 37814881›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2023

[Cardiac progenitor cells-derived exosomes alleviate myocardial injury by regulating Treg cell differentiation through the mTOR pathway in mice with myocardial infarction].

Y He, Z Li, L Shen, D Shi, S Li

Open access · greenAbstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Y HeDepartment of Pediatrics, Fourth Hospital of Changsha, Changsha Hospital of Hunan Normal University, Changsha 410006, China.
Z LiDepartment of Pediatrics, Third Xiangya Hospital, Central South University, Changsha 410013, China.
L ShenDepartment of Pediatrics, Third Xiangya Hospital, Central South University, Changsha 410013, China.
D ShiDepartment of Pediatrics, Third Xiangya Hospital, Central South University, Changsha 410013, China.
S LiDepartment of Pediatrics, Third Xiangya Hospital, Central South University, Changsha 410013, China.
Central South University · CNThird Xiangya Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the effect of cardiac progenitor cells-derived exosomes (CPCs-Exo) on Treg differentiation in mice with myocardial infarction (MI).

methodsMouse models of MI established by ligation of the left anterior descending coronary artery (LAD) were treated with CPCs-Exos, and naive CD4

resultsCompared with the control group, the mouse models of MI showed significantly increased release of LDH (

conclusionCPCs-Exos promotes the differentiation of Treg in mice with MI by modulating the mTOR signaling pathway.

Indexed as

ExosomesHeart InjuriesMyocardial InfarctionAnimalsCD28 AntigensCell DifferentiationInterleukin-10MiceStem CellsT-Lymphocytes, RegulatoryTOR Serine-Threonine KinasesCD28 AntigensInterleukin-10mTOR protein, mouseTOR Serine-Threonine Kinasescardiac progenitor cell-derived exosomesmTORmyocardial injuryTreg

Identifiers

PMID37814881
PMCPMC10563089
OpenAlexW4387472846

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.