Evidence map›Paper›PMID 37814600›Full record

ArticleInternational journal of methods in psychiatric research2023

Modeling the normal:abnormal spectrum of early childhood internalizing behaviors: A clinical-developmental approach for the Multidimensional Assessment Profiles Internalizing Dimensions.

Lauren S Wakschlag, Phillip Sherlock, Courtney K Blackwell, James L Burns, Sheila Krogh-Jespersen, Richard C Gershon, David Cella, Kristin A Buss, Joan L Luby

Abstract read
In one paragraph

Article in International journal of methods in psychiatric research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Preschool Mood Disorders: A Review of the Literature from 2017 to 2024.Child and adolescent psychiatric clinics of North America · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Measuring PROMIS® Emotional Distress in Early Childhood.Journal of pediatric psychology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lauren S WakschlagDepartment of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.ORCID 0000-0001-9511-2299
Phillip SherlockDepartment of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Courtney K BlackwellDepartment of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
James L BurnsDepartment of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Sheila Krogh-JespersenThe Institute for Innovations in Developmental Sciences, Northwestern University, Chicago, Illinois, USA.
Richard C GershonDepartment of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
David CellaDepartment of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Kristin A BussDepartment of Psychology, Pennsylvania State University, University Park, Pennsylvania, USA.
Joan L LubyWashington University School of Medicine, St. Louis, Missouri, USA.

Funding

The ECHO Measurement Core: A Framework and Resource for Assessing Environmental Exposure and Child HealthU24OD023319 · OD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Courtney K Blackwell, RICHARD GERSHON · 2016 to 2026
$43.7M
Generating an Earlier Science of When to Worry: A Neurodevelopmental, Transactional Approach to Characterizing Irritability Patterns Beginning in InfancyR01MH107652 · NIMH · NORTHWESTERN UNIVERSITY AT CHICAGO · PI WAKSCHLAG, LAUREN S · 2016 to 2021
$4.0M
NIH HHS U24 OD023319NIMH NIH HHS R01 MH107652NIMH NIH HHS R01MH107652
6 · The paper itself

Abstract

backgroundWe expanded the Multidimensional Assessment Profiles (MAPS) Scales developmental specification model to characterize the normal:abnormal spectrum of internalizing (anxious and depressive) behaviors in early childhood via the MAPS-Internalizing (MAPS-INT) scale.

methodsThe MAPS-INT item pool was generated based on clinical expertise and prior research. Analyses were conducted on a sub-sample of families (n = 183) from the diverse When to Worry early childhood sample.

resultsNormal:abnormal descriptive patterns for both anxious and depressive behaviors were consistent with prior work: (1) extremes of normative variation are abnormal when very frequent; and (2) pathognomonic indicators that most children do not engage in and are abnormal, even if infrequent. Factor analysis revealed a two-factor MAPS-INT Anxious Behaviors structure (Fearful-Worried and Separation Distress) and a unidimensional MAPS-INT Depressive Behaviors factor with good fit and good-to-excellent test-retest reliability and validity.

conclusionsWe characterized the normal:abnormal spectrum of internalizing behaviors in early childhood via the MAPS-INT. Future research in larger representative samples can replicate and extend findings, including clinical thresholds and predictive utility. The MAPS-INT helps lay the groundwork for dimensional characterization of the internalizing spectrum to advance neurodevelopmental approaches to emergent psychopathology and its earlier identification.

Indexed as

AnxietyChildChild, PreschoolHumansReproducibility of Resultsdevelopmental psychopathologyearly childhoodinternalizing problemsRDoC

Identifiers

PMID37814600
PMCPMC10654833

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.