Evidence map›Paper›PMID 37814260›Full record

ArticleMalaria journal2023

A fatal respiratory complication of malaria caused by Plasmodium vivax.

Angie R López, Ezequias B Martins, Anielle de Pina-Costa, Ana Beatriz Pacheco-Silva, Marcel T Ferreira, Roxana F Mamani, Paula J T Detepo, Otilia Lupi, Clarisse S Bressan, Guilherme A Calvet and 7 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Malaria journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

Angie R LópezInstituto Nacional de Infectologia Evandro Chagas Fiocruz, Rio de Janeiro, Brazil.
Ezequias B MartinsInstituto Nacional de Infectologia Evandro Chagas Fiocruz, Rio de Janeiro, Brazil.
Anielle de Pina-CostaInstituto Nacional de Infectologia Evandro Chagas Fiocruz, Rio de Janeiro, Brazil.
Ana Beatriz Pacheco-SilvaInstituto Nacional de Infectologia Evandro Chagas Fiocruz, Rio de Janeiro, Brazil.
Marcel T FerreiraInstituto Nacional de Infectologia Evandro Chagas Fiocruz, Rio de Janeiro, Brazil.
Roxana F MamaniInstituto Nacional de Infectologia Evandro Chagas Fiocruz, Rio de Janeiro, Brazil.
Paula J T DetepoInstituto Nacional de Infectologia Evandro Chagas Fiocruz, Rio de Janeiro, Brazil.
Otilia LupiInstituto Nacional de Infectologia Evandro Chagas Fiocruz, Rio de Janeiro, Brazil.
Clarisse S BressanInstituto Nacional de Infectologia Evandro Chagas Fiocruz, Rio de Janeiro, Brazil.
Guilherme A CalvetInstituto Nacional de Infectologia Evandro Chagas Fiocruz, Rio de Janeiro, Brazil.
Michele F B SilvaInstituto Nacional de Infectologia Evandro Chagas Fiocruz, Rio de Janeiro, Brazil.
Maria de Fátima Ferreira-da-CruzCentro de Pesquisa, Diagnóstico e Treinamento em Malária da Fiocruz e da Secretaria de Vigilância em Saúde, Ministério da Saúde, Brasília, Brazil.
Fernanda de Bruycker-NogueiraLaboratório de Flavivirus, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil.
Ana Maria B FilippisLaboratório de Flavivirus, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil.
Cláudio Tadeu Daniel-RibeiroCentro de Pesquisa, Diagnóstico e Treinamento em Malária da Fiocruz e da Secretaria de Vigilância em Saúde, Ministério da Saúde, Brasília, Brazil.
André SiqueiraInstituto Nacional de Infectologia Evandro Chagas Fiocruz, Rio de Janeiro, Brazil.
Patrícia BrasilInstituto Nacional de Infectologia Evandro Chagas Fiocruz, Rio de Janeiro, Brazil. patricia.brasil@ini.fiocruz.br.
Instituto Evandro Chagas · BRFundação Oswaldo Cruz · BRSecretaria da Saúde · BRMinistério da Saúde · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalaria is endemic and represents an important public health issue in Brazil. Knowledge of risk factors for disease progression represents an important step in preventing and controlling malaria-related complications. Reports of severe forms of Plasmodium vivax malaria are now becoming a common place, but respiratory complications are described in less than 3% of global literature on severe vivax malaria. CASE PRESENTATION: A severe respiratory case of imported vivax malaria in a previously healthy 40-year-old woman has been reported. The patient died after the fifth day of treatment with chloroquine and primaquine due to acute respiratory distress syndrome.

conclusionsRespiratory symptoms started 48 h after the initiation of anti-malarial drugs, raising the hypothesis that the drugs may have been involved in the genesis of the complication. The concept that vivax malaria is a benign disease that can sometimes result in the development of serious complications must be disseminated. This report highlights, once more, the crucial importance of malaria early diagnosis, a true challenge in non-endemic areas, where health personnel are not familiar with the disease and do not consider its diagnosis promptly.

Indexed as

AntimalarialsMalariaMalaria, VivaxAdultFemaleHumansPlasmodium vivaxPrimaquineAntimalarialsPrimaquineFatal complicationMalariaPlasmodium vivaxRespiratory

Identifiers

PMID37814260
PMCPMC10563287
OpenAlexW4387446909

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.