Evidence map›Paper›PMID 37814029›Full record

ReviewAmino acids2023

The possibilities of LOXL4 as a prognostic marker for carcinomas.

Jiaming Wang, Chaojian Chen, Jiayi Huang, Ziman Xie, Xiaoxue Chen, Ziqi Zheng, Enmin Li, Haiying Zou

Abstract readReview
PubMed Publisher
In one paragraph

Review in Amino acids, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jiaming Wang *Shantou University Medical College, Shantou, 515041, Guangdong, People's Republic of China.
Chaojian Chen *Shantou University Medical College, Shantou, 515041, Guangdong, People's Republic of China.
Jiayi HuangShantou University Medical College, Shantou, 515041, Guangdong, People's Republic of China.
Ziman XieShantou University Medical College, Shantou, 515041, Guangdong, People's Republic of China.
Xiaoxue ChenShantou University Medical College, Shantou, 515041, Guangdong, People's Republic of China.
Ziqi ZhengShantou University Medical College, Shantou, 515041, Guangdong, People's Republic of China.
Enmin LiThe Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou, 515041, Guangdong, People's Republic of China.
Haiying ZouThe Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou, 515041, Guangdong, People's Republic of China. zouhy@stu.edu.cn.
Shantou University · CNShantou University Medical College · CN

Funding

2020 Li Ka Shing Foundation Cross-Disciplinary Research Grant 2020LKSFG09BNatural Science Foundation of Guangdong Province, China 2018A030313664
6 · The paper itself

Abstract

Lysyl oxidase-like 4 (LOXL4), a member of lysyl oxidase family, is a copper and lysine tyrosylquinone-dependent amine oxidase that serves the role of catalyzing the cross-linking of elastin and collagen in the extracellular matrix. Numerous studies have shown a significant association between LOXL4 expression levels and tumor proliferation, migration, invasion and patients' prognosis and overall survival in different types of tumors. Here we review their relationship and the molecular pathogenesis behind them, aiming to explore the possibilities of LOXL4 as a prognostic marker for diverse carcinomas and provide some indications for further research in this field.

Indexed as

CarcinomaProtein-Lysine 6-OxidaseAmino Acid OxidoreductasesCollagenHumansPrognosisAmino Acid OxidoreductasesCollagenLOXL4 protein, humanProtein-Lysine 6-OxidaseCarcinomaLOXL4Prognostic marker

Identifiers

PMID37814029
OpenAlexW4387449763

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.