Evidence map›Paper›PMID 37813608›Full record

ArticleInternal medicine (Tokyo, Japan)2024

Immune-mediated Necrotizing Myopathy in a Patient with Microscopic Polyangiitis.

Daichi Umemoto, Yohei Kanzawa, Tomoko Nakamura, Ichizo Nishino, Shimpei Mizuki, Jun Ohnishi, Takahiro Nakajima, Naoto Ishimaru, Saori Kinami

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Daichi UmemotoDepartment of General Internal Medicine, Akashi Medical Center, Japan.
Yohei KanzawaDepartment of General Internal Medicine, Akashi Medical Center, Japan.
Tomoko NakamuraDepartment of Rheumatology, Akashi Medical Center, Japan.
Ichizo NishinoDepartment of Neuromuscular Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Japan.
Shimpei MizukiDepartment of General Internal Medicine, Akashi Medical Center, Japan.
Jun OhnishiDepartment of General Internal Medicine, Akashi Medical Center, Japan.
Takahiro NakajimaDepartment of General Internal Medicine, Akashi Medical Center, Japan.
Naoto IshimaruDepartment of General Internal Medicine, Akashi Medical Center, Japan.
Saori KinamiDepartment of General Internal Medicine, Akashi Medical Center, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report a case of immune-mediated necrotizing myopathy (IMNM) in a patient with microscopic polyangiitis (MPA). A 77-year-old Japanese woman presented with a 2-day history of proximal muscle weakness and myalgia, with elevated serum creatinine kinase (CK) levels. Findings of a muscle biopsy were compatible with IMNM; however, anti-signal recognition particle (SRP) and anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) antibodies were negative. She also had peripheral neuropathy with elevated serum myeloperoxidase anti-neutrophil cytoplasmic antibody titers, leading to a diagnosis of MPA. IMNM can be a pathological result of MPA muscle involvement.

Indexed as

Microscopic PolyangiitisNecrosisAgedAntibodies, Antineutrophil CytoplasmicFemaleHumansMuscle, SkeletalMuscular DiseasesAntibodies, Antineutrophil Cytoplasmicanti-neutrophil cytoplasmic antibody-associated vasculitisconnective tissue diseasesimmune-mediated necrotizing myopathymicroscopic polyangiitisseronegative

Identifiers

PMID37813608
PMCPMC11157303

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.