ArticleJournal of the American Chemical Society2023
Controlled-Radical Polymerization of α-Lipoic Acid: A General Route to Degradable Vinyl Copolymers.
Article in Journal of the American Chemical Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The trial behind it
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Who cites it
26 citing papers in PubMed.
- Mechanochemical Engineered Sulfur Copolymers Onto Group 13 and Related Fillers Through Lewis Acid-Base Pairing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Closed-Loop Recyclable Solid Polymer Electrolytes via Dynamic Lipoate Cross-Linking.Angewandte Chemie (International ed. in English) · 2026Article
- Article
- In Situ Coenzyme-Based Transformable Polymers Powder With Instant-Tough-Adhesive Properties for Emergency Hemostasis, Antibiosis, and Wound Repair.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Functional cyclic disulfides enable multi-pathway degradable polyvinyls.Chemical science · 2026Article
- 3D-Printable Nanoporous Thermosets via Disulfide-Based Polymerization-Induced Microphase Separation.Angewandte Chemie (International ed. in English) · 2026Article
- An Aggregation-Induced Polymerization Poly(Disulfide)-Drug Nanoplatform for Autoimmune Uveitis Therapy via Inhibiting the cGAS-STING Pathway.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Direct Evidence for the Sulfonium-Mediated Photopolymerization of 1,2-Dithiolanes.Journal of the American Chemical Society · 2026Article
- Degradable Vinyl-Based Polymers by Radical Ring-Opening Polymerization: A User Guide.ACS polymers Au · 2026Article
- Challenges and Opportunities for Cleavable Linkers Used in Polymer-Drug Conjugates.Journal of the American Chemical Society · 2026Review
- Synthesis of Poly(δ-valerolactone)-poly(Macromolecules · 2026Article
- Dual-Pathway Strategy for Click-Type Functionalization and Programmable Polymer Deconstruction.Macromolecules · 2026Article
- Synthesis of poly(ester disulfide)s from SNature communications · 2026Article
- Decarboxylation-Triggered Polymer Deconstruction.ACS polymers Au · 2025Review
- Evaluation of Acrylamide/α-Lipoic Acid Statistical Copolymers as Degradable Water-Soluble Kinetic Gas Hydrate Inhibitors.Polymers · 2025Article
- Hydrolytic stress degradation study and concomitant HPTLC estimation of thioctic acid and biotin in their combined capsules: greenness, blueness and whiteness assessment.BMC chemistry · 2025Article
- Introducing Disulfide Bonds into Polyester Biomaterials via Nucleophilic Thiol-yne Polymerization.ACS macro letters · 2025Article
- Oxygen-Tolerant, Red Light-Driven Controlled Synthesis of Easily Degradable and High Molecular Weight α-Lipoic Acid-Vinyl Copolymers.Angewandte Chemie (International ed. in English) · 2025Article
- Lipoic Acid Based Redox-Responsive Degradable Antimicrobial Polymers.Macromolecular rapid communications · 2025Article
- Synthesis of Degradable Polystyrene and Its Derivative with In-Chain Thioester via Radical and Cationic Copolymerizations with a Seven-Membered Benzene-Fused Thionolactone.Polymer science & technology (Washington, D.C.) · 2025Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Here, we present the synthesis and characterization of statistical and block copolymers containing α-lipoic acid (LA) using reversible addition-fragmentation chain-transfer (RAFT) polymerization. LA, a readily available nutritional supplement, undergoes efficient radical ring-opening copolymerization with vinyl monomers in a controlled manner with predictable molecular weights and low molar-mass dispersities. Because lipoic acid diads present in the resulting copolymers include disulfide bonds, these materials efficiently and rapidly degrade when exposed to mild reducing agents such as tris(2-carboxyethyl)phosphine (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.