Evidence map›Paper›PMID 37813109›Full record

ArticleAnnals of medicine2023

Incorporating intraoperative blood pressure time-series variables to assist in prediction of acute kidney injury after type a acute aortic dissection repair: an interpretable machine learning model.

Anran Dai, Zhou Zhou, Fan Jiang, Yaoyi Guo, Dorothy O Asante, Yue Feng, Kaizong Huang, Chen Chen, Hongwei Shi, Yanna Si and 1 more

Abstract read
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Article in Annals of medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

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19citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Anran DaiSchool of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China.
Zhou ZhouDepartment of Clinical Pharmacology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Fan JiangDepartment of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Yaoyi GuoDepartment of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Dorothy O AsanteDepartment of Preventive Medicine and Public Health Laboratory Science, School of Medicine, Jiangsu University, Zhenjiang, China.
Yue FengDepartment of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Kaizong HuangDepartment of Clinical Pharmacology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Chen ChenDepartment of Clinical Pharmacology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Hongwei ShiDepartment of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Yanna SiDepartment of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Jianjun ZouDepartment of Clinical Pharmacology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute kidney injury (AKI) is a common and serious complication after the repair of Type A acute aortic dissection (TA-AAD). However, previous models have failed to account for the impact of blood pressure fluctuations on predictive performance. This study aims to develop machine learning (ML) models combined with intraoperative medicine and blood pressure time-series data to improve the accuracy of early prediction for postoperative AKI risk.

methodsIndicators reflecting the duration and depth of hypotension were obtained by analyzing continuous mean arterial pressure (MAP) monitored intraoperatively with multiple thresholds (<65, 60, 55, 50) set in the study. The predictive features were selected by logistic regression and the least absolute shrinkage and selection operator (LASSO), and 4 ML models were built based on the above features. The performance of the models was evaluated by area under receiver operating characteristic curve (AUROC), calibration curve and decision curve analysis (DCA). Shapley additive interpretation (SHAP) was used to explain the prediction models.

resultsAmong the indicators reflecting intraoperative hypotension, 65 mmHg showed a statistically superior difference to other thresholds in patients with or without AKI (

conclusionWith the introduction of intraoperative blood pressure time-series variables, we have developed an interpretable XGBoost model that successfully achieve high accuracy in predicting the risk of AKI after TA-AAD repair, which might aid in the perioperative management of high-risk patients, particularly for intraoperative hemodynamic regulation.

Indexed as

Acute Kidney InjuryHypotensionBlood PressureHumansMachine LearningRetrospective StudiesAcute kidney injuryaortic dissectioncardiac surgeryintraoperative hypotensionmachine learningpredictive modelXGBoost

Identifiers

PMID37813109
PMCPMC10563625

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.