Evidence map›Paper›PMID 37812758›Full record

ReviewAnesthesiology2023

Acute Kidney Injury after Cardiac Surgery: Prediction, Prevention, and Management.

Sreekanth R Cheruku, Jacob Raphael, Javier A Neyra, Amanda A Fox

Open access · bronzeAbstract readReview
In one paragraph

Review in Anesthesiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed, 5 pooled it
29.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

102 citing papers in PubMed, 5 syntheses or guidelines pooled it, 146 citations in OpenAlex.

  1. Pooled it
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  11. Article
  12. Kidney Failure in Cardiogenic Shock.Circulation. Heart failure · 2026
    Review
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  15. Observational
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42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Sreekanth R CherukuDepartment of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center, Dallas, Texas.ORCID 0000-0003-3185-0000
Jacob RaphaelDepartment of Anesthesiology and Perioperative Medicine, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania.ORCID 0000-0003-0396-9928
Javier A NeyraCharles and Jane Pak Center for Mineral Metabolism and Clinical Research, University of Texas Southwestern Medical Center, Dallas, Texas; Department of Medicine, Division of Nephrology, University of Alabama at Birmingham, Birmingham, Alabama.ORCID 0000-0002-2817-2459
Amanda A FoxDepartment of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center, Dallas, Texas; McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, Texas.ORCID 0000-0002-7027-5806
Development Initiatives · GBSouthwestern Medical Center · USThomas Jefferson University Hospital · US

Funding

UAB-UCSD O'Brien Core Center for Acute Kidney Injury ResearchP30DK079337 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AGARWAL, ANUPAM · 2008 to 2022
$18.3M
The Southeastern Acute Kidney Injury (SEAK) Alliance for the COPE-AKI ConsortiumU01DK129989 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Javier A. Neyra, Edward D Siew · 2021 to 2026
$4.7M
Blood and Urine Biomarkers for Predicting Long-Term Adverse Kidney and Cardiovascular Outcomes after Cardiac SurgeryR01HL148448 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI FOX, AMANDA A · 2019 to 2023
$3.7M
Artificial Intelligence to Predict Outcomes in Patients with Acute Kidney Injury on Continuous Renal Replacement TherapyR01DK133539 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Girish Nitin Nadkarni, Javier A. Neyra · 2023 to 2026
$2.6M
The Relation of Soluble Klotho with Cardiovascular Disease, Chronic Kidney Disease Progression, and Blood Pressure in the Systolic Blood Pressure Intervention TrialR01DK128208 · NIDDK · TUFTS MEDICAL CENTER · PI DREW, DAVID ALAN, NEYRA, JAVIER A. · 2021 to 2025
$1.6M
NHLBI NIH HHS R01 HL148448NIDDK NIH HHS P30 DK079337NIDDK NIH HHS R01 DK128208NIDDK NIH HHS R01 DK133539NIDDK NIH HHS U01 DK129989
6 · The paper itself

Abstract

Acute kidney injury (AKI) is a common complication in cardiac surgery patients, with a reported incidence of 20 to 30%. The development of AKI is associated with worse short- and long-term mortality, and longer hospital length of stay. The pathogenesis of cardiac surgery-associated AKI is poorly understood but likely involves an interplay between preoperative comorbidities and perioperative stressors. AKI is commonly diagnosed by using increases in serum creatinine or decreased urine output and staged using a standardized definition such as the Kidney Disease Improving Global Outcomes classification. Novel biomarkers under investigation may provide earlier detection and better prediction of AKI, enabling mitigating therapies early in the perioperative period. Recent clinical trials of cardiac surgery patients have demonstrated the benefit of goal-directed oxygen delivery, avoidance of hyperthermic perfusion and specific fluid and medication strategies. This review article highlights both advances and limitations regarding the prevention, prediction, and treatment of cardiac surgery-associated AKI.

Indexed as

Acute Kidney InjuryCardiac Surgical ProceduresBiomarkersComorbidityHumansPostoperative ComplicationsRisk FactorsBiomarkers

Identifiers

PMID37812758
PMCPMC10841304
OpenAlexW4387447689

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.