ArticleEuropean geriatric medicine2023
Optimizing pharmacotherapy and deprescribing strategies in older adults living with multimorbidity and polypharmacy: EuGMS SIG on pharmacology position paper.
Article in European geriatric medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Effectiveness and safety of chronic diuretic use in older adults: an umbrella review of recently published systematic reviews and meta-analyses of randomized-controlled trials.European geriatric medicine · 2025Pooled it
- The effects of diuretic deprescribing in adult patients: A systematic review to inform an evidence-based diuretic deprescribing guideline.British journal of clinical pharmacology · 2025Pooled it
- Lifestyle interventions and medication burden in older adults: insights from the Lifestyle Intervention and Independence for Elders (LIFE) and the Sarcopenia and Physical fRailty iN older people: multi-componenT Treatment strategies (SPRINTT) trials.European geriatric medicine · 2025Trial
- Pharmacist-led deprescribing of cardiovascular and diabetes medication within a clinical medication review: the LeMON study (Less Medicines in Older Patients in the Netherlands), a cluster randomized controlled trial.International journal of clinical pharmacy · 2025Trial
- Effects of proactive healthcare on pain, physical and activities of daily living functioning in vulnerable older adults with chronic pain: a pragmatic clinical trial with one- and two-year follow-up.European geriatric medicine · 2024Trial
- Drug-Drug Interactions in Nursing Home Residents With vs Without Dementia.Journal of the American Medical Directors Association · 2026Observational
- Same Patients, Different Health Care Systems-Revisited. Geriatric Care Models in the U.S., Canada, and Europe.Journal of the American Geriatrics Society · 2026Article
- Evaluation of a Pharmacist-Led Intervention Focused on the Deprescribing of Cardiovascular and Antidiabetic Medication in Older Patients With Polypharmacy: Patients' and Pharmacists' Experiences.Basic & clinical pharmacology & toxicology · 2026Article
- Potentially Inappropriate Prescription and Its Association with Index Hospitalization: A Multicenter, Cross-Sectional Study Using TIME Criteria.Drugs & aging · 2026Observational
- [Concepts to improve medication safety in older patients].Innere Medizin (Heidelberg, Germany) · 2026Review
- Factors associated with medication self-management performance in the "Ability to Self-administer Medication in Non-demented In-hospital Patients" (ABLYMED) study.BMC geriatrics · 2026Observational
- Multi-Institutional Drug Use Patterns in Hospitalized Older Patients: Retrospective Cross-Sectional Study.JMIR medical informatics · 2026Article
- Applying a multidisciplinary intervention for drug adequacy in an intermediate care hospital (AMIDA-ICH): study protocol of a complex intervention trial.Frontiers in medicine · 2026Article
- Polypharmacy appropriateness in Italian Long-Term Care Facilities: the nationwide prescription day point survey.Aging clinical and experimental research · 2025Article
- Article
- Hippocratic considerations about statin treatment for patients over 75 years of age.European geriatric medicine · 2025Article
- Medication Management in Patients With Polypharmacy in Primary Care: A Scoping Review of Clinical Practice Guidelines.Journal of evidence-based medicine · 2025Article
- Multicomponent intervention to tailor prescriptions to patients with dementia in an intermediate care hospital: pre-post quasi experimental study.BMC geriatrics · 2025Article
- Deprescribing oral antidiabetics in elderly patients: Do electronic leaflets across the world address it?Exploratory research in clinical and social pharmacy · 2024Article
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Corrections and comments
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Authors and funding
21 authors at 17 institutions in 10 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inappropriate polypharmacy is highly prevalent among older adults and presents a significant healthcare concern. Conducting medication reviews and implementing deprescribing strategies in multimorbid older adults with polypharmacy are an inherently complex and challenging task. Recognizing this, the Special Interest Group on Pharmacology of the European Geriatric Medicine Society has compiled evidence on medication review and deprescribing in older adults and has formulated recommendations to enhance appropriate prescribing practices. The current evidence supports the need for a comprehensive and widespread transformation in education, guidelines, research, advocacy, and policy to improve the management of polypharmacy in older individuals. Furthermore, incorporating deprescribing as a routine aspect of care for the ageing population is crucial. We emphasize the importance of involving geriatricians and experts in geriatric pharmacology in driving, and actively participating in this transformative process. By doing so, we can work towards achieving optimal medication use and enhancing the well-being of older adults in the generations to come.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.