Observational studyIntensive care medicine2023
Self-reported symptoms experienced by intensive care unit patients: a prospective observational multicenter study.
Observational study in Intensive care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Demographic, perioperative, biochemical and illness-severity predictors of thirst in critically ill patients: a systematic review and meta-analysis.Internal medicine journal · 2026Pooled it
- Risk factors of thirst amongst critically ill and patients undergoing surgery: a systematic review and meta-analysis.Irish journal of medical science · 2026Pooled it
- Prevalence, risk factors, and treatment methods of thirst in critically ill patients: A systematic review and meta-analysis.PloS one · 2025Pooled it
- Thirst level trajectories and influencing factors in critically ill patients based on a group-based trajectory model: A prospective observational study.International journal of nursing studies advances · 2026Article
- Persistent Thirst and Its Clinical Correlates in Critically Ill Adults: A Prospective Observational Study.Nursing in critical care · 2026Observational
- Early Markers of Systemic Inflammation are not Related to Pain Burden After Aneurysmal Subarachnoid Hemorrhage: A Multicenter Observational Study.Neurocritical care · 2026Observational
- Quantifying the recollection of discomfort and emotional suffering during a stay in intensive care: development and validation of the EXPRIM questionnaire : EXPRIM: quantification of discomfort experienced during an ICU stay.Journal of patient-reported outcomes · 2026Article
- Dyspnea is related to clinical outcomes in patients weaning from invasive mechanical ventilation with tracheostomy: a multicenter prospective study.Critical care (London, England) · 2026Observational
- Impact of an interventional thirst bundle on thirst discomfort and dry mouth in nasogastric tube-fed patients: Quasi-experimental time-series study.Journal of education and health promotion · 2026Article
- Thirst in End-Stage Liver Disease: From Symptom Disregard to a Multidisciplinary Clinical Pathway and Future Perspectives: A Narrative Review.Journal of multidisciplinary healthcare · 2026Review
- Epidemiology of pain, delirium, psychiatric disorders, discomfort and sedation-analgesia management in the intensive care unit: a one-day nationwide study.Critical care (London, England) · 2025Article
- Virtual reality for relaxation in intensive care unit patients: feasibility, acceptability and intervention adaptation.Pilot and feasibility studies · 2025Article
- Prevalence and factors associated with thirst in children after congenital heart disease surgery: a cross-sectional study.BMC pediatrics · 2025Article
- Review
- Thirst in ICU Patients: A Scoping Review.Cureus · 2025Review
- Challenges in Thirst Management for Intubated Patients in the ICU: A Qualitative Study of Healthcare Provider and Patient Perspectives.Journal of multidisciplinary healthcare · 2025Article
- Development of safety protocols for managing thirst in post-extubated and tracheostomized patients.Revista latino-americana de enfermagem · 2025Article
- Lived Experiences of Conscious Intubated Patients in the Intensive Care Units: A Qualitative Phenomenological Study in Iran.BMJ open · 2024Article
- Impact of sensory stimulations on thirst in critically ill mechanically ventilated patients.Intensive care medicine · 2024Article
- Breathlessness assessment, management and impact in the intensive care unit: a rapid review and narrative synthesis.Annals of intensive care · 2024Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study is to describe the prevalence, intensity and distress of five symptoms in intensive care unit (ICU) patients and to investigate possible predictive factors associated with symptom intensity.
methodsThis is a prospective cohort study of ICU patients. A symptom questionnaire (i.e., Patient Symptom Survey) was used to describe the prevalence, intensity and distress of pain, thirst, anxiousness, tiredness, and shortness of breath over seven ICU days. Associations between symptom intensity and possible predictive factors were assessed using the general estimating equation (GEE) model.
resultsOut of 603 eligible patients, 353 (Sample 2) were included in the present study. On the first ICU day, 195 patients (Sample 1) reported thirst as the most prevalent symptom (66%), with the highest mean intensity score (6.13, 95% confidence interval (CI) [5.7-6.56]). Thirst was the most prevalent (64%) and most intense (mean score 6.05, 95%CI [5.81-6.3]) symptom during seven days in the ICU. Anxiousness was the most distressful (mean score 5.24, 95%CI [4.32-6.15]) symptom on the first day and during seven days (mean score 5.46, 95%CI [4.95-5.98]). During seven days, analgesic administration and sepsis diagnosis were associated with increased thirst intensity. Older age and being mechanically ventilated were associated with decreased pain intensity, and analgesic administration was associated with increased pain intensity. Family visits and female gender were associated with increased intensity of anxiousness and shortness of breath, respectively.
conclusionsSelf-reporting ICU patients experienced a high and consistent symptom burden across seven days. Certain variables were associated with the degree of symptom intensity, but further research is required to better understand these associations.
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