Evidence map›Paper›PMID 37811746›Full record

ArticleMolecular and cellular biology2023

Persistent Acetylation of Histone H3 Lysine 56 Compromises the Activity of DNA Replication Origins.

Roch Tremblay, Yosra Mehrjoo, Oumaima Ahmed, Antoine Simoneau, Mary E McQuaid, El Bachir Affar, Corey Nislow, Guri Giaever, Hugo Wurtele

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular and cellular biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Chromatin architecture sets origin licensing capacity.bioRxiv : the preprint server for biology · 2026
    Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Roch TremblayMaisonneuve-Rosemont Hospital Research Center, Montreal, Québec, Canada.
Yosra MehrjooMaisonneuve-Rosemont Hospital Research Center, Montreal, Québec, Canada.
Oumaima AhmedMaisonneuve-Rosemont Hospital Research Center, Montreal, Québec, Canada.
Antoine SimoneauMaisonneuve-Rosemont Hospital Research Center, Montreal, Québec, Canada.
Mary E McQuaidMaisonneuve-Rosemont Hospital Research Center, Montreal, Québec, Canada.
El Bachir AffarMaisonneuve-Rosemont Hospital Research Center, Montreal, Québec, Canada.
Corey NislowDepartment of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
Guri GiaeverDepartment of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
Hugo WurteleMaisonneuve-Rosemont Hospital Research Center, Montreal, Québec, Canada.ORCID 0000-0002-5733-1711
Hôpital Maisonneuve-Rosemont · CAUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In

Indexed as

Saccharomyces cerevisiae ProteinsSirtuinsAcetylationCell Cycle ProteinsDNA ReplicationHistone DeacetylasesHistonesLysineMutationProtein Serine-Threonine KinasesReplication OriginSaccharomyces cerevisiaeCDC7 protein, S cerevisiaeCell Cycle ProteinsHistone DeacetylasesHistonesHst3 protein, S cerevisiaeHst4 protein, S cerevisiaeLysineProtein Serine-Threonine KinasesSaccharomyces cerevisiae ProteinsSirtuinschromatin structureDNA damage responseDNA replicationhistone H3 lysine 56 acetylationHst3 and Hst4S. cerevisiaesirtuins

Identifiers

PMID37811746
PMCPMC10791153
OpenAlexW4387440379

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.