Evidence map›Paper›PMID 37811091›Full record

ReviewAnnals of medicine and surgery (2012)2023

Lack of association of the alpha-ketoglutarate-dependent dioxygenase (FTO) gene polymorphisms with pulmonary tuberculosis risk: a systematic review and meta-analysis.

Pratik Lamichhane, Maha Rahim Qureshi, Nabila Islam, Sailakshmn Sanipini, Vakeanand Gopaul, Shakira Dilfazeer Razick, Anushka Agrawal, Ramces Falfan-Valencia

Open access · diamondAbstract readReview
In one paragraph

Review in Annals of medicine and surgery (2012), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 67% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 7 countries.

Pratik LamichhaneMaharajgunj Medical Campus, Institute of Medicine, Kathmandu, Nepal.
Maha Rahim QureshiBaqai Medical University, Karachi, Pakistan.
Nabila IslamMymensingh Medical College, Mymensingh, Bangladesh.
Sailakshmn SanipiniXavier University School of Medicine, Oranjestad, Aruba.
Vakeanand GopaulWashington University of Health and Science, San Pedro, Belize.
Shakira Dilfazeer RazickWyckoff Heights Medical Center, New York, NY.
Anushka AgrawalMaharajgunj Medical Campus, Institute of Medicine, Kathmandu, Nepal.
Ramces Falfan-ValenciaInstituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City, Mexico.
Tribhuvan University Teaching Hospital · NPBaqai Medical University · PKInstituto Nacional de Enfermedades Respiratorias · MXMymensingh Medical College Hospital · BDUniversity of Aruba · AWUniversity of Belize · BZWyckoff Heights Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Our meta-analysis aims to explore the association of two single nucleotide variants; rs9939609 and rs8050136, within the FTO gene with risk of pulmonary tuberculosis (PTB). Methods: The association of two single nucleotide variants with PTB in three genetic models was evaluated using pooled odds ratios (ORs) with 95% CIs. Results: No significant association was observed between the rs9939609 polymorphism and PTB when assuming an allelic model (OR: 1.10; 95% CI: 0.85-1.41; Conclusion: There might be no association between the rs9939609 and rs8050136 variants in the FTO gene, and the risk of PTB.

Indexed as

FTO genepolymorphismrs8050136rs9939609single nucleotide varianttuberculosis

Identifiers

PMID37811091
PMCPMC10553135
OpenAlexW4386257344

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.