Evidence map›Paper›PMID 37811014›Full record

ArticleAnnals of medicine and surgery (2012)2023

Progressive multifocal leukoencephalopathy in the background of chlorambucil treated chronic lymphocytic leukemia: a case report from Nepal.

Bishal Dhakal, Binit Upadhaya Regmi, Ram Chandra Subedi, Sushil Joshi, Bishnu Deep Pathak, Kanchan Bogati, Sunil Baniya, Peter Neupane, Raju Paudel

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Annals of medicine and surgery (2012), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 4 countries.

Bishal DhakalNepalese Army Institute of Health and Sciences, College of Medicine.
Binit Upadhaya RegmiJibjibe Primary Health Care Center, Rasuwa, Nepal.
Ram Chandra SubediCgrandy International Hospital.
Sushil JoshiDodhara Primary Health Care Center.
Bishnu Deep PathakJibjibe Primary Health Care Center, Rasuwa, Nepal.
Kanchan BogatiPatan Academy of Health Sciences, Kathmandu.
Sunil BaniyaPatan Academy of Health Sciences, Kathmandu.
Peter NeupaneJibjibe Primary Health Care Center, Rasuwa, Nepal.
Raju PaudelNepalese Army Institute of Health and Sciences, College of Medicine.
Nepalese Army Institute of Health Services · NPPatan Academy of Health Sciences · NPAmhara Regional Health Bureau · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Progressive multifocal leukoencephalopathy is a rare manifestation in itself. Although many immunosuppressive states are associated with the disease, its occurrence in the setting of chronic lymphocytic leukaemia treated with chemotherapy is seldom reported to date. Case presentation: A 67-year-old woman with known chronic lymphocytic leukaemia who was previously receiving chlorambucil treatment was identified as having progressive multifocal leukoencephalopathy; her prognosis is currently good. Clinical discussion: Although a rare disease in an immunocompromised setting, progressive multifocal leukoencephalopathy often leads to a grave outcome. However, the authors describe a case with a good prognosis to date. Conclusion: Progressive multifocal leukoencephalopathy should be in differentials in immunocompromised patients with dementia. Given that the later prognosis of the disease is unpredictable, an earlier diagnosis would be better for immunological reconstitution.

Indexed as

chlorambucilchronic lymphocytic leukaemiaimmunosuppressionprognosisprogressive multifocal leukoencephalopathy

Identifiers

PMID37811014
PMCPMC10553170
OpenAlexW4385838847

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.