Evidence map›Paper›PMID 37810705›Full record

ArticleACS omega2023

Exploring Antibacterial Properties of Bioactive Compounds Isolated from

Govindaraj Sriragavi, Murthy Sangeetha, Munusamy Santhakumar, Elumalai Lokesh, Mohanam Nithyalakshmi, Chanduveetil Ahamed Saleel, Ramasamy Balagurunathan

Abstract read
In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Identifying Antimicrobial Agents fromBiotech (Basel (Switzerland)) · 2025
    Article
  4. Article
  5. Review
  6. Review
  7. Metabolic Comparison and Molecular Networking of Antimicrobials inInternational journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Govindaraj SriragaviActinobacterial Research Laboratory, Department of Microbiology, Periyar University, Salem 636011, Tamilnadu, India.ORCID https://orcid.org/0009-0003-1627-5914
Murthy SangeethaActinobacterial Research Laboratory, Department of Microbiology, Periyar University, Salem 636011, Tamilnadu, India.
Munusamy SanthakumarActinobacterial Research Laboratory, Department of Microbiology, Periyar University, Salem 636011, Tamilnadu, India.
Elumalai LokeshActinobacterial Research Laboratory, Department of Microbiology, Periyar University, Salem 636011, Tamilnadu, India.
Mohanam NithyalakshmiActinobacterial Research Laboratory, Department of Microbiology, Periyar University, Salem 636011, Tamilnadu, India.
Chanduveetil Ahamed SaleelDepartment of Mechanical Engineering, College of Engineering, King Khalid University, P.O. Box 394, Abha 61421, Saudi Arabia.
Ramasamy BalagurunathanActinobacterial Research Laboratory, Department of Microbiology, Periyar University, Salem 636011, Tamilnadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing concern over multidrug resistance in pathogens has led to an ongoing search for novel antibiotics derived from soil actinobacteria. In this current investigation, actinobacteria were isolated from the rhizosphere of bamboo plants collected within the Megamalai forest of the Western Ghats in the Theni zone of Tamil Nadu, India. These actinobacteria were subjected to characterization, and their growth conditions were optimized to enhance the production of bioactive compounds. To assess antibacterial properties, the isolated Actinobacteria underwent testing using the agar plug method. The strain exhibiting notable antibacterial activity underwent further characterization through 16s rRNA gene sequencing and subsequent phylogenetic analysis. Employing response surface methodology (RSM), cultural conditions were fine-tuned. Bioactive compounds were extracted from the culture medium using ethyl acetate, and their antibacterial and antioxidant effects were evaluated through disc diffusion and DPPH radical scavenging methods, respectively. Ethyl acetate extracts were analyzed by using FT-IR and GC-MS techniques. In total, nine strains of Actinobacteria were isolated from the rhizosphere soil of bamboo. Among these, strain BS-16 displayed remarkable antibacterial activity against three strains:

Identifiers

PMID37810705
PMCPMC10552487

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.