Evidence map›Paper›PMID 37810685›Full record

ArticleACS omega2023

Identification of Indicative Gut Microbial Guilds in a Natural Aging Mouse Model.

Yen-Chun Koh, Lee-Han Kuo, Yen-Chen Tung, Monthana Weerawatanakorn, Min-Hsiung Pan

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Yen-Chun KohInstitute of Food Science and Technology, National Taiwan University, Taipei 10617, Taiwan.ORCID https://orcid.org/0000-0001-7683-873X
Lee-Han KuoInstitute of Food Science and Technology, National Taiwan University, Taipei 10617, Taiwan.
Yen-Chen TungDepartment of Food Science, National Ilan University, Yilan 26041, Taiwan.ORCID https://orcid.org/0000-0001-9055-5509
Monthana WeerawatanakornDepartment of Agro-Industry, Faculty of Agriculture, Natural Resources and Environment, Naresuan University, Phitsanulok 65000, Thailand.
Min-Hsiung PanInstitute of Food Science and Technology, National Taiwan University, Taipei 10617, Taiwan.ORCID https://orcid.org/0000-0002-5188-7030
National Taiwan University · TWAsia University · TWNaresuan University · THNational Ilan University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gut microbial dysbiosis during later life may contribute to health conditions, possibly due to an increase in intestinal permeability, immune changes, and systemic inflammation. Mouse models have been employed to determine the influence of gut microbes on aging; however, suitable gut microbial indicators are currently lacking. Therefore, this study aimed to determine the gut microbial indicators and their potential guilds in a natural aging mouse model. In agreement with previous studies, alpha diversity indices-including observed OTUs, ACE, Chao1, and Simpson-were significantly lower in aged mice than in younger mice. The results of beta diversity analysis revealed the compositional differences between young and aged mice, and the MRPP, ANOSIM, and Adonis tests indicated that the results were representative. By employing ANCOM and LEfSe analyses,

Identifiers

PMID37810685
PMCPMC10552476
OpenAlexW4386924337

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.