Evidence map›Paper›PMID 37810281›Full record

ArticleAdvanced functional materials2023

Additive Manufacturing of Engineered Living Materials with Bio-augmented Mechanical Properties and Resistance to Degradation.

Gokce Altin-Yavuzarslan, Sierra M Brooks, Shuo-Fu Yuan, James O Park, Hal S Alper, Alshakim Nelson

Abstract read
In one paragraph

Article in Advanced functional materials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Lithography-based 3D printing of hydrogels.Nature reviews bioengineering · 2025
    Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gokce Altin-YavuzarslanMolecular Engineering and Sciences Institute, University of Washington, Seattle, Washington 98195, United States.
Sierra M BrooksMcKetta Department of Chemical Engineering, The University of Texas at Austin, Austin, TX, USA.
Shuo-Fu YuanInstitute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX, USA.
James O ParkDepartment of Surgery, University of Washington, Seattle, Washington 98195, United States.
Hal S AlperMcKetta Department of Chemical Engineering, The University of Texas at Austin, Austin, TX, USA.
Alshakim NelsonMolecular Engineering and Sciences Institute, University of Washington, Seattle, Washington 98195, United States.

Funding

3D Printed Engineered Living Materials for Drug DeliveryR21EB031256 · NIBIB · UNIVERSITY OF WASHINGTON · PI NELSON, ALSHAKIM · 2022 to 2024
$589k
NIBIB NIH HHS R21 EB031256
6 · The paper itself

Abstract

Engineered living materials (ELMs) combine living cells with polymeric matrices to yield unique materials with programmable functions. While the cellular platform and the polymer network determine the material properties and applications, there are still gaps in our ability to seamlessly integrate the biotic (cellular) and abiotic (polymer) components into singular material, then assemble them into devices and machines. Herein, we demonstrated the additive-manufacturing of ELMs wherein bioproduction of metabolites from the encapsulated cells enhanced the properties of the surrounding matrix. First, we developed aqueous resins comprising bovine serum albumin (BSA) and poly(ethylene glycol diacrylate) (PEGDA) with engineered microbes for vat photopolymerization to create objects with a wide array of 3D form factors. The BSA-PEGDA matrix afforded hydrogels that were mechanically stiff and tough for use in load-bearing applications. Second, we demonstrated the continuous

Indexed as

Additive ManufacturingBioaugmentationEngineered living materialsHydrogelsMicroorganisms

Identifiers

PMID37810281
PMCPMC10553028

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.