Evidence map›Paper›PMID 37810233›Full record

ArticleiScience2023

Lipid droplets modulate proteostasis, SQST-1/SQSTM1 dynamics, and lifespan in

Anita V Kumar, Joslyn Mills, Wesley M Parker, Joshua A Leitão, Diego I Rodriguez, Sandrine E Daigle, Celeste Ng, Rishi Patel, Joseph L Aguilera, Joseph R Johnson and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Autophagy: A Double-Edged Sword in the Aging ofInternational journal of molecular sciences · 2026
    Review
  3. Review
  4. Article
  5. Review
  6. Lipid droplets and cellular lipid flux.Nature cell biology · 2024
    Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Anita V KumarDepartment of Molecular Biology, Cell Biology and Biochemistry, Brown University, 185 Meeting Street, Providence, RI 02912, USA.
Joslyn MillsDepartment of Molecular Biology, Cell Biology and Biochemistry, Brown University, 185 Meeting Street, Providence, RI 02912, USA.
Wesley M ParkerDepartment of Molecular Biology, Cell Biology and Biochemistry, Brown University, 185 Meeting Street, Providence, RI 02912, USA.
Joshua A LeitãoDepartment of Molecular Biology, Cell Biology and Biochemistry, Brown University, 185 Meeting Street, Providence, RI 02912, USA.
Diego I RodriguezDepartment of Molecular Biology, Cell Biology and Biochemistry, Brown University, 185 Meeting Street, Providence, RI 02912, USA.
Sandrine E DaigleNew Brunswick Center for Precision Medicine, 27 rue Providence, Moncton, NB E1C 8X3, Canada.
Celeste NgDepartment of Molecular Biology, Cell Biology and Biochemistry, Brown University, 185 Meeting Street, Providence, RI 02912, USA.
Rishi PatelDepartment of Molecular Biology, Cell Biology and Biochemistry, Brown University, 185 Meeting Street, Providence, RI 02912, USA.
Joseph L AguileraDepartment of Molecular Biology, Cell Biology and Biochemistry, Brown University, 185 Meeting Street, Providence, RI 02912, USA.
Joseph R JohnsonDepartment of Molecular Biology, Cell Biology and Biochemistry, Brown University, 185 Meeting Street, Providence, RI 02912, USA.
Shi Quan WongDepartment of Molecular Biology, Cell Biology and Biochemistry, Brown University, 185 Meeting Street, Providence, RI 02912, USA.
Louis R LapierreDepartment of Molecular Biology, Cell Biology and Biochemistry, Brown University, 185 Meeting Street, Providence, RI 02912, USA.
Brown University · USUniversité de Moncton · CA

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Regulation of the transcription factor HLH-30/TFEB in agingR01AG051810 · NIA · BROWN UNIVERSITY · PI LAPIERRE, LOUIS RENE · 2016 to 2020
$1.9M
Role of LIPL-4 in lysosomal lipolysis and agingR00AG042494 · NIA · BROWN UNIVERSITY · PI LAPIERRE, LOUIS RENE · 2015 to 2017
$730k
Investigating nucleo-cytoplasmic partitioning in Alzheimer's disease and agingR21AG068922 · NIA · BROWN UNIVERSITY · PI LAPIERRE, LOUIS RENE · 2020 to 2021
$437k
NIA NIH HHS R00 AG042494NIA NIH HHS R01 AG051810NIA NIH HHS R21 AG068922NIH HHS P40 OD010440
6 · The paper itself

Abstract

In several long-lived

Indexed as

BiochemistryBiological sciences

Identifiers

PMID37810233
PMCPMC10551902
OpenAlexW4386793970

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.