Evidence map›Paper›PMID 37809399›Full record

ArticleHeliyon2023

Antimetastatic activity of seongsanamide B in γ-irradiated human lung cancer.

Ga-Hee Ryoo, Geum Jin Kim, Ah-Reum Han, Chang Hyun Jin, Hunmin Lee, Joo-Won Nam, Hyukjae Choi, Chan-Hun Jung

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ga-Hee RyooAdvanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup-si, Jeollabuk-do, 56212, South Korea.
Geum Jin KimCollege of Pharmacy, Yeungnam University, Gyeongsan-si, Gyeongsangbuk-do, 38541, South Korea.
Ah-Reum HanAdvanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup-si, Jeollabuk-do, 56212, South Korea.
Chang Hyun JinAdvanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup-si, Jeollabuk-do, 56212, South Korea.
Hunmin LeeCollege of Pharmacy, Yeungnam University, Gyeongsan-si, Gyeongsangbuk-do, 38541, South Korea.
Joo-Won NamCollege of Pharmacy, Yeungnam University, Gyeongsan-si, Gyeongsangbuk-do, 38541, South Korea.
Hyukjae ChoiCollege of Pharmacy, Yeungnam University, Gyeongsan-si, Gyeongsangbuk-do, 38541, South Korea.
Chan-Hun JungJeonju AgroBio-Materials Institute, Jeonju-si, Jeollabuk-do, 54810, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer, which has a high incidence and mortality rates, often metastasizes and exhibits resistance to radiation therapy. Seongsanamide B has conformational features that suggest it has therapeutic potential; however, its antitumor activity has not yet been reported. We evaluated the possibility of seongsanamide B as a radiation therapy efficiency enhancer to suppress γ-irradiation-induced metastasis in non-small cell lung cancer. Seongsanamide B suppressed non-small cell lung cancer cell migration and invasion caused by γ-irradiation. Furthermore, it suppressed γ-irradiation-induced upregulation of Bcl-X

Indexed as

Lung cancerMetastasisRadiation therapy enhancerSeongsanamide B

Identifiers

PMID37809399
PMCPMC10559954

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.