Evidence map›Paper›PMID 37809056›Full record

ArticlePhysics and imaging in radiation oncology2023

A geometry and dose-volume based performance monitoring of artificial intelligence models in radiotherapy treatment planning for prostate cancer.

Geert De Kerf, Michaël Claessens, Fadoua Raouassi, Carole Mercier, Daan Stas, Piet Ost, Piet Dirix, Dirk Verellen

Open access · goldAbstract read
In one paragraph

Article in Physics and imaging in radiation oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.3field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Geert De KerfDepartment of Radiation Oncology, Iridium Netwerk, Wilrijk (Antwerp), Belgium.
Michaël ClaessensDepartment of Radiation Oncology, Iridium Netwerk, Wilrijk (Antwerp), Belgium.
Fadoua RaouassiDepartment of Radiation Oncology, Iridium Netwerk, Wilrijk (Antwerp), Belgium.
Carole MercierDepartment of Radiation Oncology, Iridium Netwerk, Wilrijk (Antwerp), Belgium.
Daan StasDepartment of Radiation Oncology, Iridium Netwerk, Wilrijk (Antwerp), Belgium.
Piet OstDepartment of Radiation Oncology, Iridium Netwerk, Wilrijk (Antwerp), Belgium.
Piet DirixDepartment of Radiation Oncology, Iridium Netwerk, Wilrijk (Antwerp), Belgium.
Dirk VerellenDepartment of Radiation Oncology, Iridium Netwerk, Wilrijk (Antwerp), Belgium.
University of Antwerp · BEIridium Kankernetwerk · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Purpose: Clinical Artificial Intelligence (AI) implementations lack ground-truth when applied on real-world data. This study investigated how combined geometrical and dose-volume metrics can be used as performance monitoring tools to detect clinically relevant candidates for model retraining. Materials and Methods: Fifty patients were analyzed for both AI-segmentation and planning. For AI-segmentation, geometrical (Standard Surface Dice 3 mm and Local Surface Dice 3 mm) and dose-volume based parameters were calculated for two organs (bladder and anorectum) to compare AI output against the clinically corrected structure. A Local Surface Dice was introduced to detect geometrical changes in the vicinity of the target volumes, while an Absolute Dose Difference (ADD) evaluation increased focus on dose-volume related changes. AI-planning performance was evaluated using clinical goal analysis in combination with volume and target overlap metrics. Results: The Local Surface Dice reported equal or lower values compared to the Standard Surface Dice (anorectum: (0.93 ± 0.11) vs (0.98 ± 0.04); bladder: (0.97 ± 0.06) vs (0.98 ± 0.04)). The ADD metric showed a difference of (0.9 ± 0.8)Gy for the anorectum Conclusions: Combining dose-volume and geometrical metrics allowed detection of clinically relevant changes, applied to both auto-segmentation and auto-planning output and the Local Surface Dice was more sensitive to local changes compared to the Standard Surface Dice. This monitoring is able to evaluate AI behavior in clinical practice and allows candidate selection for active learning.

Indexed as

Artificial intelligenceClinical metricsDeep Learning PlanningDeep Learning SegmentationPerformance monitoringSBRT prostate

Identifiers

PMID37809056
PMCPMC10550805
OpenAlexW4386945783

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.