Evidence map›Paper›PMID 37808964›Full record

ArticleJAAD international2023

Polyautoimmunity in patients with cutaneous lupus erythematosus: A nationwide sex- and age-matched cohort study from Denmark.

Christoffer S Graven-Nielsen, Ida V Vittrup, Anna J Kragh, Fredrik Lund, Sofie Bliddal, Kristian Kofoed, Salome Kristensen, Allan Stensballe, Claus H Nielsen, Ulla Feldt-Rasmussen and 2 more

Open access · goldAbstract read
In one paragraph

Article in JAAD international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Christoffer S Graven-NielsenCenter for Rheumatology Research Aalborg (CERRA), Aalborg University Hospital, Aalborg, Denmark.
Ida V VittrupCenter for Rheumatology Research Aalborg (CERRA), Aalborg University Hospital, Aalborg, Denmark.
Anna J KraghCenter for Rheumatology Research Aalborg (CERRA), Aalborg University Hospital, Aalborg, Denmark.
Fredrik LundCenter for Rheumatology Research Aalborg (CERRA), Aalborg University Hospital, Aalborg, Denmark.
Sofie BliddalDepartment of Medical Endocrinology and Metabolism, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.
Kristian KofoedSkin Clinic Rødovre, Rødovre, Denmark.
Salome KristensenCenter for Rheumatology Research Aalborg (CERRA), Aalborg University Hospital, Aalborg, Denmark.
Allan StensballeDepartment of Health Science and Technology, Aalborg University, Denmark.
Claus H NielsenInstitute of Inflammation Research, Center for Rheumatology and Spine Diseases, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.
Ulla Feldt-RasmussenDepartment of Medical Endocrinology and Metabolism, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.
René CordtzCenter for Rheumatology Research Aalborg (CERRA), Aalborg University Hospital, Aalborg, Denmark.
Lene DreyerCenter for Rheumatology Research Aalborg (CERRA), Aalborg University Hospital, Aalborg, Denmark.
Aalborg University Hospital · DKAalborg University · DKRigshospitalet · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Polyautoimmunity is defined as having 2 or more autoimmune diseases. Little is known about polyautoimmunity in patients with cutaneous lupus erythematosus (CLE). Objectives: To estimate prevalence and 5-year incidence of non-lupus erythematosus (LE) autoimmune diseases in patients with CLE. Methods: Patients with CLE were identified In the Danish National Patient Registry and each patient was age- and sex-matched with 10 general population controls. Outcome information on non-LE autoimmune diseases was obtained by register-linkage between Danish National Patient Registry and the National Prescription Register. The risk ratio (RR) for prevalent non-LE autoimmune disease at time of CLE diagnosis was calculated in modified Poisson regression; and hazard ratios (HRs) for incident non-LE autoimmune disease were estimated in Cox regression analyses. Results: Overall, 1674 patients with CLE had a higher prevalence of a non-LE autoimmune disease than the comparators (18.5 vs 7.9%; RR 2.4; 95% CI, 2.1 to 2.6). Correspondingly, the cumulative incidence of a non-LE autoimmune disease during 5 years of follow-up was increased for the patients with CLE: HR 3.5 (95% CI, 3.0 to 4.0). Limitations: Risk of detection and misclassification bias, mainly pertaining to the CLE group. Conclusion: Patients with CLE had higher prevalence and 5-year cumulative incidence of a non-LE autoimmune disease than the general population.

Indexed as

autoimmune diseasescutaneous lupus erythematosusepidemiologypolyautoimmunitythyroid autoimmunity

Identifiers

PMID37808964
PMCPMC10550802
OpenAlexW4386157720

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.