Evidence map›Paper›PMID 37808963›Full record

ArticleJAAD international2023

Characteristics, treatment patterns, health care resource utilization and costs in patients with bullous pemphigoid: A retrospective analysis of US health insurance claims data.

Heide A Stirnadel-Farrant, Xiao Xu, Justin Kwiatek, Priya Jain, Juliana Meyers, Sean Candrilli, Daniel Mines, Catherine J Datto

Open access · goldAbstract read
In one paragraph

Article in JAAD international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Heide A Stirnadel-FarrantBioPharmaceuticals Medical, AstraZeneca, Cambridge, UK.
Xiao XuBioPharmaceuticals Medical, AstraZeneca, Gaithersburg, Maryland.
Justin KwiatekBioPharmaceuticals Medical, AstraZeneca, Gaithersburg, Maryland.
Priya JainBioPharmaceuticals Medical, AstraZeneca, Cambridge, UK.
Juliana MeyersRTI Health Solutions, Research Triangle Park, North Carolina.
Sean CandrilliRTI Health Solutions, Research Triangle Park, North Carolina.
Daniel MinesRTI Health Solutions, Research Triangle Park, North Carolina.
Catherine J DattoLate-Stage Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland.
AstraZeneca (United States) · USAstraZeneca (United Kingdom) · GBRTI Health Solutions · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Real-world data describing the impact of incident bullous pemphigoid (BP) on patients and health care resource utilization (HCRU) are limited. Objective: To examine characteristics, treatment patterns, HCRU, and costs for incident BP. Methods: Retrospective analysis of 2015 to 2019 US health insurance claims for patients ≥18 years with an incident BP diagnosis. Patients with BP were matched to those without on demographic and clinical characteristics. Statistics were descriptive. Results: The mean Charlson Comorbidity Index score was higher for patients with BP ( Limitations: Diagnoses were based on billing codes. HCRU claims data may not reflect the true number of encounters. Conclusion: Incident BP is associated with considerable morbidity, HCRU, and costs. More effective, targeted treatments are needed to improve quality of life, while minimizing exposure to systemic corticosteroids.

Indexed as

antibioticsautoimmune diseaseblistering skin diseasebullous pemphigoidburden of diseaseclinical characteristicscomorbiditycostshealth care resource utilizationopioidssteroidstreatment

Identifiers

PMID37808963
PMCPMC10550796
OpenAlexW4380201633

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.