Evidence map›Paper›PMID 37808931›Full record

ArticleHealth science reports2023

Treatment of

Mohamed Hichem Loghmari, Firas Aissaoui, Arwa Guediche, Wided Bouhlel, Mejda Zakhama, Nabil B Chaabene, Amel Rehaiem, Nouha Ben Abdeljalil, Manel Njima, Abdelfetteh Zakhama and 3 more

Open access · goldAbstract read
In one paragraph

Article in Health science reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 2 citations in OpenAlex.

  1. [Evidence-Based Guidelines for the Diagnosis and Treatment ofThe Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2026
    Guideline
  2. Guideline
  3. Review
  4. Article
  5. Treatment ofHealth science reports · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Mohamed Hichem LoghmariDepartment of Hepato-Gastroenterology Fattouma Bourguiba University Hospital Monastir Tunisia.ORCID https://orcid.org/0000-0002-9676-7761
Firas AissaouiDepartment of Hepato-Gastroenterology Fattouma Bourguiba University Hospital Monastir Tunisia.
Arwa GuedicheDepartment of Hepato-Gastroenterology Fattouma Bourguiba University Hospital Monastir Tunisia.
Wided BouhlelDepartment of Hepato-Gastroenterology Fattouma Bourguiba University Hospital Monastir Tunisia.
Mejda ZakhamaDepartment of Hepato-Gastroenterology Fattouma Bourguiba University Hospital Monastir Tunisia.
Nabil B ChaabeneDepartment of Hepato-Gastroenterology Fattouma Bourguiba University Hospital Monastir Tunisia.
Amel RehaiemDepartment of Hepato-Gastroenterology Fattouma Bourguiba University Hospital Monastir Tunisia.
Nouha Ben AbdeljalilDepartment of Pathological Anatomy Fattouma Bourguiba University Hospital Monastir Tunisia.
Manel NjimaDepartment of Pathological Anatomy Fattouma Bourguiba University Hospital Monastir Tunisia.
Abdelfetteh ZakhamaDepartment of Pathological Anatomy Fattouma Bourguiba University Hospital Monastir Tunisia.
Yosr KadriMicrobiology Laboratory Fattouma Bourguiba University Hospital Monastir Tunisia.
Maha MastouriMicrobiology Laboratory Fattouma Bourguiba University Hospital Monastir Tunisia.
Leila SaferDepartment of Hepato-Gastroenterology Fattouma Bourguiba University Hospital Monastir Tunisia.
Hospital Fatuma Bourguiba Monastir · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Successful Methods: A parallel double-blind randomized controlled trial was conducted. The diagnosis of Hp infection was made by pathological examination of gastric biopsies. Patients were randomly assigned to two treatment groups: either QC (esomeprazole 80 mg, amoxicillin 2000 mg, clarithromycin 1000 mg, and metronidazole 1000 mg daily) or triple therapy (esomeprazole 80 mg, amoxicillin 2000 mg, and clarithromycin 1000 mg daily in divided doses) for 14 days. The efficacy of the treatment is defined by Hp eradication attested by a negative breath test performed 6 weeks after the completion of treatment. Treatment outcomes were compared using the chi-square test, while binary logistic regression identified predictors of treatment failure. Results: Ninety-two patients were included. Forty-two patients belonged to the QC group and 50 to the TT group. No significant difference was noted between the two groups concerning the rate of Hp eradication either by intention to treat (81% vs. 72% respectively, Conclusion: There was no significant difference in the rate of HP eradication between the QC and the 14-day triple therapy. Neither regimen should be used topically because of their low eradication rates.

Indexed as

breath testeradicationHelicobacter pyloriquadruple concomitant therapytriple therapy

Identifiers

PMID37808931
PMCPMC10551283
OpenAlexW4387361464

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.