ArticlemedRxiv : the preprint server for health sciences2023
The Impact of Intermittent Hypoxemia on Type 1 Retinopathy of Prematurity in Preterm Infants.
Samaneh Rabienia Haratbar, Li Chen, Qiang Cheng, Dara Singh, Faraneh Fathi, Mehrana Mohtasebi, Xuhui Liu, Abhijit Patwardhan, Prasad Bhandary, Henrietta S Bada and 2 more
Open access · greenAbstract readPreprint
In one paragraphArticle in medRxiv : the preprint server for health sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
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2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 3 citations in OpenAlex.
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4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
12 authors at 2 institutions in 2 countries.
Samaneh Rabienia HaratbarDepartment of Biomedical Engineering, University of Kentucky.
Li ChenBiostatistics and Bioinformatics Shared Resource Facility, Markey Cancer Center, University of Kentucky.
Qiang ChengInstitute for Biomedical Informatics, Department of Internal Medicine and Department of Computer Science.
Dara SinghDepartment of Biomedical Engineering, University of Kentucky.
Faraneh FathiDepartment of Biomedical Engineering, University of Kentucky.
Mehrana MohtasebiDepartment of Biomedical Engineering, University of Kentucky.
Xuhui LiuDepartment of Biomedical Engineering, University of Kentucky.
Abhijit PatwardhanDepartment of Biomedical Engineering, University of Kentucky.
Prasad BhandaryDivision of Neonatology, Department of Pediatrics, University of Kentucky.
Henrietta S BadaDivision of Neonatology, Department of Pediatrics, University of Kentucky.
Guoqiang YuDepartment of Biomedical Engineering, University of Kentucky.
Elie G Abu JawdehDivision of Neonatology, Department of Pediatrics, University of Kentucky.
University of Kentucky · USInstitute for Medical Informatics and Biostatistics · CH
Funding
Kentucky Center for Clinical and Translational ScienceUL1TR001998 · NCATS · UNIVERSITY OF KENTUCKY · PI HARTMANN, KATHERINE E, KERN, PHILIP A · 2016 to 2025
$34.2MSupplement to Prebiotics Intervention to Reduce Alzheimer's Disease Risk via Brain-Gut Axis in an APOE4 Mouse ModelRF1AG062480 · NIA · UNIVERSITY OF MISSOURI-COLUMBIA · PI LIN, AI-LING · 2019 to 2020
$3.6MNoninvasive Noncontact High-Density Optical Imaging of Neonatal Intraventricular HemorrhageR01HD101508 · NICHD · UNIVERSITY OF KENTUCKY · PI YU, GUOQIANG · 2020 to 2024
$2.7MPerioperative Diffuse Optical Imaging of Tissue Blood Flow and Oxygenation for Optimization of Mastectomy Skin Flap ViabilityR01EB028792 · NIBIB · UNIVERSITY OF KENTUCKY · PI YU, GUOQIANG · 2020 to 2024
$1.9MHigh-density optical tomography of cerebral blood flow and metabolism in small animalsR41NS122722 · NINDS · BIOPTICSTECHNOLOGY, LLC · PI YU, GUOQIANG · 2021 to 2022
$688kSystemic Mediators and Biomarkers of Injury in Preterm Infants with Intermittent HypoxemiaK23HD109471 · NICHD · UT SOUTHWESTERN MEDICAL CENTER · PI Elie G Abu Jawdeh · 2023 to 2026
$644kContinuous and Longitudinal Monitoring of Cerebral Blood Flow and Metabolism in Freely Moving RodentsR56NS117587 · NINDS · UNIVERSITY OF KENTUCKY · PI YU, GUOQIANG · 2020 to 2020
$613kA Multiscale Multimodal Diffuse Optical Device for Early Detection of Preclinical Alzheimer’s DiseaseR21HD091118 · NICHD · UNIVERSITY OF KENTUCKY · PI YU, GUOQIANG · 2018 to 2019
$568kImplementing a novel, multimodal technique for monitoring cerebrovascular hemodynamics in mice as a diagnostic and prognostic tool for single and repeated mild TBIR21NS114771 · NINDS · UNIVERSITY OF KENTUCKY · PI SAATMAN, KATHRYN E · 2020 to 2020
$421kNCATS NIH HHS UL1 TR001998NIA NIH HHS RF1 AG062480NIBIB NIH HHS R01 EB028792NICHD NIH HHS K23 HD109471NICHD NIH HHS R01 HD101508NICHD NIH HHS R21 HD091118NINDS NIH HHS R21 NS114771NINDS NIH HHS R41 NS122722NINDS NIH HHS R56 NS117587
6 · The paper itselfAbstract
Background: Intermittent hypoxemia (IH) may influence retinopathy of prematurity (ROP) development in preterm infants, however, previous studies had mixed results. This study aims to assess the influence and evaluate the predictive ability of IH measures on Type 1 ROP, a stage beyond which ROP treatment is indicated. Methods: IH was quantified by continuously monitoring oxygen saturation (SpO Results: Univariate analyses suggested that IH measures are greater in infants with Type 1 ROP and are predictive of Type 1 ROP development. Multivariable logistic regression analyses revealed that cumulative IH of longer duration during certain postnatal periods are associated with Type 1 ROP development after adjusting for gestational age (GA) or birth weight (BW). Although area under the curve (AUC) analyses revealed added predictivity of cumulative IH variables above GA or BW, these increments in AUC were not statistically significant. Conclusions: The duration of IH events was associated with Type 1 ROP development. Interventions for reducing the duration of IH events may potentially improve ROP outcomes.
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PMID37808800
PMCPMC10557831
OpenAlexW4387073952
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