ArticlebioRxiv : the preprint server for biology2024
A Small Multidrug Resistance Transporter in
Andrea K Wegrzynowicz, William J Heelan, Sydnye P Demas, Maxwell S McLean, Jason M Peters, Katherine A Henzler-Wildman
Open access · greenAbstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 1 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
6 authors at 1 institution in 1 country.
Andrea K WegrzynowiczDepartment of Biochemistry, University of Wisconsin-Madison, Madison WI.
William J HeelanPharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison.
Sydnye P DemasDepartment of Biochemistry, University of Wisconsin-Madison, Madison WI.
Maxwell S McLeanDepartment of Biochemistry, University of Wisconsin-Madison, Madison WI.
Jason M PetersPharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison.
Katherine A Henzler-WildmanDepartment of Biochemistry, University of Wisconsin-Madison, Madison WI.
University of Wisconsin–Madison · US
Funding
Biotechnology Training ProgramT32GM135066 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI SCOTT M. COYLE, BRIAN G FOX · 2020 to 2026
$7.0MNMR User Program at NMRFAMR24GM141526 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Katherine Anne Henzler-Wildman · 2021 to 2026
$6.4MTRANSPORT MECHANISM OF THE MULTIDRUG RESISTANCE EFFLUX PROTEIN, EMRER01GM095839 · NIGMS · WASHINGTON UNIVERSITY · PI HENZLER-WILDMAN, KATHERINE ANNE · 2011 to 2020
$3.1MMolecular Mechanisms of Channels and TransportersR35GM141748 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Katherine Anne Henzler-Wildman · 2021 to 2026
$2.7MInducing susceptibility with a small multidrug resistance transporter from P. aeruginosaF31AI169825 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI WEGRZYNOWICZ, ANDREA KILLIAN · 2022 to 2023
$60kNIAID NIH HHS F31 AI169825NIGMS NIH HHS R01 GM095839NIGMS NIH HHS R24 GM141526NIGMS NIH HHS R35 GM141748NIGMS NIH HHS T32 GM135066
6 · The paper itselfAbstract
Small Multidrug Resistance (SMR) transporters are key players in the defense of multidrug-resistant pathogens to toxins and other homeostasis-perturbing compounds. However, recent evidence demonstrates that EmrE, an SMR from
Indexed as
Multidrug effluxproton-motive forcesusceptibilitytransportuniport
Identifiers
PMID37808795
PMCPMC10557727
OpenAlexW4387220577
What OpenQuestion holds
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LicenceCC BY-NC-ND
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