Evidence map›Paper›PMID 37808795›Full record

ArticlebioRxiv : the preprint server for biology2024

A Small Multidrug Resistance Transporter in

Andrea K Wegrzynowicz, William J Heelan, Sydnye P Demas, Maxwell S McLean, Jason M Peters, Katherine A Henzler-Wildman

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Andrea K WegrzynowiczDepartment of Biochemistry, University of Wisconsin-Madison, Madison WI.
William J HeelanPharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison.
Sydnye P DemasDepartment of Biochemistry, University of Wisconsin-Madison, Madison WI.
Maxwell S McLeanDepartment of Biochemistry, University of Wisconsin-Madison, Madison WI.
Jason M PetersPharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison.
Katherine A Henzler-WildmanDepartment of Biochemistry, University of Wisconsin-Madison, Madison WI.
University of Wisconsin–Madison · US

Funding

Biotechnology Training ProgramT32GM135066 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI SCOTT M. COYLE, BRIAN G FOX · 2020 to 2026
$7.0M
NMR User Program at NMRFAMR24GM141526 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Katherine Anne Henzler-Wildman · 2021 to 2026
$6.4M
TRANSPORT MECHANISM OF THE MULTIDRUG RESISTANCE EFFLUX PROTEIN, EMRER01GM095839 · NIGMS · WASHINGTON UNIVERSITY · PI HENZLER-WILDMAN, KATHERINE ANNE · 2011 to 2020
$3.1M
Molecular Mechanisms of Channels and TransportersR35GM141748 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Katherine Anne Henzler-Wildman · 2021 to 2026
$2.7M
Inducing susceptibility with a small multidrug resistance transporter from P. aeruginosaF31AI169825 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI WEGRZYNOWICZ, ANDREA KILLIAN · 2022 to 2023
$60k
NIAID NIH HHS F31 AI169825NIGMS NIH HHS R01 GM095839NIGMS NIH HHS R24 GM141526NIGMS NIH HHS R35 GM141748NIGMS NIH HHS T32 GM135066
6 · The paper itself

Abstract

Small Multidrug Resistance (SMR) transporters are key players in the defense of multidrug-resistant pathogens to toxins and other homeostasis-perturbing compounds. However, recent evidence demonstrates that EmrE, an SMR from

Indexed as

Multidrug effluxproton-motive forcesusceptibilitytransportuniport

Identifiers

PMID37808795
PMCPMC10557727
OpenAlexW4387220577

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.