Evidence map›Paper›PMID 37808790›Full record

ArticlebioRxiv : the preprint server for biology2025

Multimodal delineation of a layer of effector function among exhausted CD8 T cells in tumors.

Arja Ray, Molly Bassette, Kenneth H Hu, Lomax F Pass, Tristan Courau, Bushra Samad, Alexis Combes, Vrinda Johri, Brittany Davidson, Katherine Wai and 4 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Arja RayDepartment of Pathology, University of California, San Francisco, CA 94143, USA.ORCID 0000-0003-2305-2324
Molly BassetteDepartment of Pathology, University of California, San Francisco, CA 94143, USA.
Kenneth H HuDepartment of Pathology, University of California, San Francisco, CA 94143, USA.
Lomax F PassDepartment of Pathology, University of California, San Francisco, CA 94143, USA.
Tristan CourauDepartment of Pathology, University of California, San Francisco, CA 94143, USA.
Bushra SamadImmunoX Initiative, University of California, San Francisco, CA 94143, USA.
Alexis CombesDepartment of Pathology, University of California, San Francisco, CA 94143, USA.
Vrinda JohriImmunoX Initiative, University of California, San Francisco, CA 94143, USA.
Brittany DavidsonImmunoX Initiative, University of California, San Francisco, CA 94143, USA.
Katherine WaiDepartment of Otolaryngology Head and Neck Surgery, University of California, San Francisco, CA 94143, USA.
Patrick HaDepartment of Otolaryngology Head and Neck Surgery, University of California, San Francisco, CA 94143, USA.
Grace HernandezDepartment of Anatomy, University of California, San Francisco, CA 94143, USA.
Itzia Zaleta-LinaresDepartment of Pathology, University of California, San Francisco, CA 94143, USA.
Matthew F KrummelDepartment of Pathology, University of California, San Francisco, CA 94143, USA.ORCID 0000-0001-7915-3533
University of California, San Francisco · US

Funding

MOLECULAR AND CELLULAR IMMUNOLOGYT32AI007334 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CYSTER, JASON G · 1988 to 2023
$11.0M
The Tumor Microenvironment Niche of Type I conventional Dendritic CellsR01CA197363 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MATTHEW F KRUMMEL · 2017 to 2026
$4.5M
CONTROL OF T CELL SYNAPSE STABILIZATION AND SIGNALINGR37AI052116 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MATTHEW F KRUMMEL · 2023 to 2026
$2.5M
NCI NIH HHS R01 CA197363NIAID NIH HHS R37 AI052116NIAID NIH HHS T32 AI007334
6 · The paper itself

Abstract

The anti-tumor function of CD8 T cells is limited through well-established pathways of T cell exhaustion (T

Identifiers

PMID37808790
PMCPMC10557647
OpenAlexW4387124093

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.