Evidence map›Paper›PMID 37808706›Full record

ArticlebioRxiv : the preprint server for biology2025

QPPLab: A generally applicable software package for detecting, analyzing, and visualizing large-scale quasiperiodic spatiotemporal patterns (QPPs) of brain activity.

Nan Xu, Behnaz Yousefi, Nmachi Anumba, Theodore J LaGrow, Xiaodi Zhang, Shella Keilholz

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Nan XuWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, United States.ORCID 0000-0002-3900-3220
Behnaz YousefiWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, United States.
Nmachi AnumbaWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, United States.
Theodore J LaGrowElectrical and Computer Engineering, Georgia Tech, Atlanta, GA, United States.
Xiaodi ZhangWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, United States.
Shella KeilholzWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, United States.
Georgia Institute of Technology · US

Funding

Contribution of Ultra Low Frequency LFPs to Functional MRIR01NS078095 · NINDS · EMORY UNIVERSITY · PI KEILHOLZ, SHELLA D · 2012 to 2022
$3.4M
Crossing space and time: uncovering the nonlinear dynamics of multimodal and multiscale brain activityR01EB029857 · NIBIB · EMORY UNIVERSITY · PI KEILHOLZ, SHELLA D, STANLEY, GARRETT B. · 2020 to 2021
$1.3M
Time-varying spatiotemporal causal interactions in the functional brain networksK99NS123113 · NINDS · GEORGIA INSTITUTE OF TECHNOLOGY · PI XU, NAN · 2023 to 2024
$184k
NIBIB NIH HHS R01 EB029857NINDS NIH HHS K99 NS123113NINDS NIH HHS R01 NS078095
6 · The paper itself

Abstract

Quasi-periodic patterns (QPPs) are prominent spatiotemporal brain dynamics observed in functional neuroimaging data, reflecting the alternation of high and low activity across brain regions and their propagation along cortical gradients. QPPs have been linked to neural processes such as attention, arousal fluctuations, and cognitive function. Despite their significance, existing QPP analysis tools are limited by study-specific parameters and complex workflows. To address these challenges, we present

Indexed as

functional MRIInfraslow activityquasiperiodic patternsspatiotemporal brain dynamics

Identifiers

PMID37808706
PMCPMC10557593
OpenAlexW4387011128

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.