ArticleNeurophotonics2023
Acute hypoxia elicits prefrontal oxygenation asymmetry in young adults.
Article in Neurophotonics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 4 citations in OpenAlex.
- Amnestic Mild Cognitive Impairment Does Not Alter Cerebrocortical Oxygenation Dynamics During Acute Hypoxia-Reoxygenation in Older Adults.Biomedicines · 2025Article
- Acute Effect of Moderate-Intensity Interval Intradialytic Exercise on Cerebral Oxygenation in Hemodialysis Patients: A Randomized Crossover Trial.Journal of the American Society of Nephrology : JASN · 2025Article
- Cluster Headache and Hypoxia: Breathing New Life into an Old Theory, with Novel Implications.Neurology international · 2024Review
- Relationship of Cognitive Function with Oxygenated Haemoglobin Concentration Difference Between the Left and Right Prefrontal Cortex During 40-Min Moderate-Intensity Exercise.Advances in experimental medicine and biology · 2024Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Significance: Cerebrovascular reactivity can be evaluated by prefrontal cortex (PFC) hemodynamic responses and oxygenation changes secondary to hypoxia using near-infrared spectroscopy (NIRS). However, whether there are hemispheric differences in these NIRS-determined PFC hemodynamic responses and oxygenation changes remains unknown. Aim: This study was performed to determine whether there are differences in the PFC hemodynamic responses and oxygenation changes secondary to hypoxia between the left and right frontal poles (FPL and FPR, respectively). Approach: Fifteen young men participated in the study. During conduction of an isocapnic hypoxia protocol with a 10-min hypoxic phase at partial pressure of end-tidal oxygen ( Results: In response to hypoxia, the HR increased, oxy-Hb decreased, deoxy-Hb increased, total-Hb increased above baseline, and Conclusions: NIRS-determined hemodynamic responses and oxygenation changes secondary to hypoxia might not simply reflect the direct effect of hypoxia on cerebral vessels. Although there is no hemispheric difference in the PFC hemodynamic responses to hypoxia as in total-Hb, PFC oxygenation asymmetry occurs in young adults.
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