Evidence map›Paper›PMID 37808269›Full record

ArticleMedComm2023

Single-cell RNA sequencing reveals the effects of capsaicin in the treatment of sepsis-induced liver injury.

Qian Zhang, Jing Liu, Jing Shen, Jinhuan Ou, Yin Kwan Wong, Lulin Xie, Jingnan Huang, Chunting Zhang, Chunjin Fu, Junhui Chen and 7 more

Open access · goldAbstract read
In one paragraph

Article in MedComm, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. FPR1-dependent Pro-inflammatory Ccl4Respiratory research · 2025
    Article
  8. Article
  9. Article
  10. Sepsis: An Overview of Current Therapies and Future Research.Journal of clinical practice and research · 2025
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 2 countries.

Qian ZhangDepartment of Critical Medicine, and Shenzhen Clinical Research Centre for Geriatrics Shenzhen People's Hospital First Affiliated Hospital of Southern University of Science and Technology Second Clinical Medicine College of Jinan University Shenzhen Guangdong China.
Jing LiuDepartment of Critical Medicine, and Shenzhen Clinical Research Centre for Geriatrics Shenzhen People's Hospital First Affiliated Hospital of Southern University of Science and Technology Second Clinical Medicine College of Jinan University Shenzhen Guangdong China.
Jing ShenDepartment of Oncology Shenzhen People's Hospital The First Affiliated Hospital Southern University of Science and Technology Shenzhen Guangdong China.
Jinhuan OuDepartment of Critical Medicine, and Shenzhen Clinical Research Centre for Geriatrics Shenzhen People's Hospital First Affiliated Hospital of Southern University of Science and Technology Second Clinical Medicine College of Jinan University Shenzhen Guangdong China.
Yin Kwan WongDepartment of Physiology Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore.
Lulin XieDepartment of Critical Medicine, and Shenzhen Clinical Research Centre for Geriatrics Shenzhen People's Hospital First Affiliated Hospital of Southern University of Science and Technology Second Clinical Medicine College of Jinan University Shenzhen Guangdong China.
Jingnan HuangDepartment of Critical Medicine, and Shenzhen Clinical Research Centre for Geriatrics Shenzhen People's Hospital First Affiliated Hospital of Southern University of Science and Technology Second Clinical Medicine College of Jinan University Shenzhen Guangdong China.
Chunting ZhangDepartment of Critical Medicine, and Shenzhen Clinical Research Centre for Geriatrics Shenzhen People's Hospital First Affiliated Hospital of Southern University of Science and Technology Second Clinical Medicine College of Jinan University Shenzhen Guangdong China.
Chunjin FuDepartment of Critical Medicine, and Shenzhen Clinical Research Centre for Geriatrics Shenzhen People's Hospital First Affiliated Hospital of Southern University of Science and Technology Second Clinical Medicine College of Jinan University Shenzhen Guangdong China.
Junhui ChenDepartment of Critical Medicine, and Shenzhen Clinical Research Centre for Geriatrics Shenzhen People's Hospital First Affiliated Hospital of Southern University of Science and Technology Second Clinical Medicine College of Jinan University Shenzhen Guangdong China.
Jiayun ChenState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Artemisinin Research Center, and Institute of Chinese Materia Medica China Academy of Chinese Medical Sciences Beijing China.
Xueling HeState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Artemisinin Research Center, and Institute of Chinese Materia Medica China Academy of Chinese Medical Sciences Beijing China.
Fei ShiDepartment of Infectious Disease Shenzhen People's Hospital The First Affiliated Hospital Southern University of Science and Technology Shenzhen Guangdong China.
Piao LuoDepartment of Critical Medicine, and Shenzhen Clinical Research Centre for Geriatrics Shenzhen People's Hospital First Affiliated Hospital of Southern University of Science and Technology Second Clinical Medicine College of Jinan University Shenzhen Guangdong China.
Ping GongDepartment of Emergency Shenzhen People's Hospital The First Affiliated Hospital Southern University of Science and Technology Shenzhen City Guangdong Province China.
Xueyan LiuDepartment of Critical Medicine, and Shenzhen Clinical Research Centre for Geriatrics Shenzhen People's Hospital First Affiliated Hospital of Southern University of Science and Technology Second Clinical Medicine College of Jinan University Shenzhen Guangdong China.
Jigang WangDepartment of Critical Medicine, and Shenzhen Clinical Research Centre for Geriatrics Shenzhen People's Hospital First Affiliated Hospital of Southern University of Science and Technology Second Clinical Medicine College of Jinan University Shenzhen Guangdong China.ORCID https://orcid.org/0000-0002-0575-0105
Jinan University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNSouthern University of Science and Technology · CNNational University of Singapore · SGSheng Jing Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis is a difficult-to-treat systemic condition in which liver dysfunction acts as both regulator and target. However, the dynamic response of diverse intrahepatic cells to sepsis remains poorly characterized. Capsaicin (CAP), a multifunctional chemical derived from

Indexed as

capsaicininflammationscRNA‐seqsepsis

Identifiers

PMID37808269
PMCPMC10556204
OpenAlexW4387397678

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.