Evidence map›Paper›PMID 37807996›Full record

ReviewGynecology and minimally invasive therapy

Obstructed Hemivagina and Ipsilateral Renal Anomaly Syndrome: A Systematic Review about Diagnosis and Surgical Management.

Graziella Moufawad, Andrea Giannini, Ottavia D'Oria, Antonio Simone Laganà, Vito Chiantera, Aline Khazzaka, Ghida Maziad, Elena Nasr, Vanessa Geagea, Marwa Al Jardali and 1 more

Open access · diamondAbstract readReview
In one paragraph

Review in Gynecology and minimally invasive therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Clinical features and surgical options of obstructed hemivagina and ipsilateral renal agenesis (OHVIRA) syndrome: A systematic review and a meta-analysis of prevalence.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
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  16. Prenatal Detection of Intra-Abdominal Cyst Leading to Neonatal Diagnosis of OHVIRA Syndrome.Pediatrics international : official journal of the Japan Pediatric Society
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Graziella MoufawadDepartment of Obstetrics and Gynaecology, School of Medicine, Lebanese American University, Beirut, Lebanon.
Andrea GianniniDepartment of Medical and Surgical Sciences and Translational Medicine, Sapienza University, Rome, Italy.
Ottavia D'OriaDepartment of Medical and Surgical Sciences and Translational Medicine, Sapienza University, Rome, Italy.
Antonio Simone LaganàUnit of Gynecologic Oncology, ARNAS "Civico - Di Cristina - Benfratelli", Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy.
Vito ChianteraUnit of Gynecologic Oncology, ARNAS "Civico - Di Cristina - Benfratelli", Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy.
Aline KhazzakaDepartment of Obstetrics and Gynaecology, Laboratory of Science and Research, Saint Joseph University, Beirut, Lebanon.
Ghida MaziadDepartment of Obstetrics and Gynaecology, School of Medicine, Lebanese American University, Beirut, Lebanon.
Elena NasrDepartment of Obstetrics and Gynaecology, School of Medicine, Lebanese American University, Beirut, Lebanon.
Vanessa GeageaDepartment of Obstetrics and Gynaecology, School of Medicine, Lebanese American University, Beirut, Lebanon.
Marwa Al JardaliDepartment of Obstetrics and Gynaecology, School of Medicine, Lebanese American University, Beirut, Lebanon.
Zaki SleimanDepartment of Obstetrics and Gynaecology, School of Medicine, Lebanese American University, Beirut, Lebanon.
Lebanese American University · LBSapienza University of Rome · ITUniversity of Palermo · ITSaint Joseph University · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obstructed hemivagina and ipsilateral renal agenesis (OHVIRA) syndrome is a rare congenital defect of the Müllerian ducts characterized by uterus didelphys, unilateral obstructed hemivagina, and ipsilateral renal agenesis. The aim of this systematic review is to summarize the main symptoms and presentation of the OHVIRA syndrome, as well as the different types of management, fertility, and obstetrical outcomes. A comprehensive search was performed in PubMed, EMBASE, SCOPUS, and Web of Science databases since inception to May 1, 2022, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. After duplicate records removed, the search strategy retrieved 103 articles. The full texts of 73 articles further were assessed for eligibility, and 44 studies were finally included in the systematic review. The mainstay surgical treatment of OHVIRA syndrome is usually a minimally invasive vaginal approach to remove the septum. Ultrasound-guided hysteroscopic resection and laparoscopic resection of the septum have been described as alternatives. Considering the feasibility of minimally invasive approach for the management of the syndrome, laparotomy should be avoided as much as possible and considered only in selected cases.

Indexed as

Fertility-sparing surgeryMüllerian anomaliesobstructed hemivagina and ipsilateral renal agenesis syndromepelvic pain

Identifiers

PMID37807996
PMCPMC10553600
OpenAlexW4385719228

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.