Evidence map›Paper›PMID 37807941›Full record

ArticleThe Kaohsiung journal of medical sciences2023

The gut microbiota metabolite butyrate mitigates MPTP/MPP

Li-Li Ji, Ting-Ting Huang, Lun-Lin Mao, Yuan-Feng Xu, Wen-Ya Chen, Wei-Wei Wang, Li-Hui Wang

Open access · goldAbstract read
In one paragraph

Article in The Kaohsiung journal of medical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. The gut microbiota metabolite butyrate mitigates MPTP/MPPThe Kaohsiung journal of medical sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Li-Li JiDepartment of Neurology, Jiangsu University Affiliated with Wujin Hospital (Wujin Clinical College of Xuzhou Medical University), Changzhou, China.
Ting-Ting HuangDepartment of Neurology, Jiangsu University Affiliated with Wujin Hospital (Wujin Clinical College of Xuzhou Medical University), Changzhou, China.
Lun-Lin MaoDepartment of Neurology, Jiangsu University Affiliated with Wujin Hospital (Wujin Clinical College of Xuzhou Medical University), Changzhou, China.
Yuan-Feng XuDepartment of Neurology, Jiangsu University Affiliated with Wujin Hospital (Wujin Clinical College of Xuzhou Medical University), Changzhou, China.
Wen-Ya ChenDepartment of Neurology, Jiangsu University Affiliated with Wujin Hospital (Wujin Clinical College of Xuzhou Medical University), Changzhou, China.
Wei-Wei WangSchool of Basic Medicine, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Li-Hui WangDepartment of Neurology, Jiangsu University Affiliated with Wujin Hospital (Wujin Clinical College of Xuzhou Medical University), Changzhou, China.ORCID https://orcid.org/0009-0007-6545-4344
Jiangsu University · CNXuzhou Medical College · CN

Funding

Changzhou Sci and Tech Program CJ20210011
6 · The paper itself

Abstract

Butyrate (BU), a gut microbiota-derived metabolite, has been reported to play a neuroprotective role in Parkinson's disease (PD). However, the specific molecular mechanism of BU has not been fully interpreted. This work aimed to verify the protective effects of BU against MPTP/MPP

Indexed as

Gastrointestinal MicrobiomeMPTP PoisoningNeuroprotective AgentsParkinson DiseaseAnimalsButyratesMiceMice, Inbred C57BLPC12 CellsRatsSignal TransductionButyratesNeuroprotective Agentsbutyrategut microbiota metaboliteJAK2/STAT3Parkinson's disease

Identifiers

PMID37807941
PMCPMC11895885
OpenAlexW4387440020

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.