Evidence map›Paper›PMID 37807813›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023

Fluorinated-Squaramide Covalent Organic Frameworks for High-Performance and Interference-Free Extraction of Synthetic Cannabinoids.

Yueru Shi, Ruolun Xu, Shaohan Wang, Juan Zheng, Fang Zhu, Qingkun Hu, Junlong Huang, Gangfeng Ouyang

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Synthesis of a Highly Fluorescent Quinoxalino[2,3-The Journal of organic chemistry · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yueru ShiMOE Key Laboratory of Aquatic Product Safety/KLGHEI of Environment and Energy Chemistry, School of Chemistry, Sun Yat-sen University, Guangzhou, 510275, China.ORCID https://orcid.org/0000-0002-8336-8905
Ruolun XuAnti-Drug Technology Center of Guangdong Province, Guangdong Provincial Key Laboratory of Psychoactive Substances Monitoring and Safety, Guangzhou, 510535, China.
Shaohan WangMOE Key Laboratory of Aquatic Product Safety/KLGHEI of Environment and Energy Chemistry, School of Chemistry, Sun Yat-sen University, Guangzhou, 510275, China.
Juan ZhengMOE Key Laboratory of Aquatic Product Safety/KLGHEI of Environment and Energy Chemistry, School of Chemistry, Sun Yat-sen University, Guangzhou, 510275, China.ORCID https://orcid.org/0000-0002-3020-2426
Fang ZhuMOE Key Laboratory of Aquatic Product Safety/KLGHEI of Environment and Energy Chemistry, School of Chemistry, Sun Yat-sen University, Guangzhou, 510275, China.ORCID https://orcid.org/0000-0002-6939-9975
Qingkun HuAnti-Drug Technology Center of Guangdong Province, Guangdong Provincial Key Laboratory of Psychoactive Substances Monitoring and Safety, Guangzhou, 510535, China.
Junlong HuangSGS-CSTC Standards Technical Services Co., Ltd., Guangzhou, 510670, China.ORCID https://orcid.org/0000-0002-4381-4915
Gangfeng OuyangMOE Key Laboratory of Aquatic Product Safety/KLGHEI of Environment and Energy Chemistry, School of Chemistry, Sun Yat-sen University, Guangzhou, 510275, China.ORCID https://orcid.org/0000-0002-0797-6036

Funding

China Postdoctoral Science Foundation 2021M691090China Postdoctoral Science Foundation 2021M693605Guangzhou Science and Technology Planning Project 202201011547National Natural Science Foundation of China 22036003National Natural Science Foundation of China 22076222National Natural Science Foundation of China 22208118National Natural Science Foundation of China 22276222Natural Science Foundation of Guangdong Province 2022A1515010051
6 · The paper itself

Abstract

Synthetic cannabinoids (SCs), one of the largest groups of new psychoactive substances (NPSs), have emerged as a significant public health threat in different regions worldwide. Analyzing SCs in water samples is critical to estimate their consumption and control. However, due to their low background concentration and the coexistence of complex matrix, the selective and effective enrichment of SCs is still challenging. In this study, a series of fluorinated-squaramide-based covalent organic frameworks (COF: FSQ-2, FSQ-3, and FSQ-4) are synthesized, and the as-prepared FSQ-4 exhibits strong affinity to different SCs. The proper pore size (1.4 nm) and pre-located functional groups (hydrogen-bond donors, hydrogen-bond acceptors, and fluorophilic segments) work synergistically for efficient SCs capture. Remarkably, when coupled FSQ-4 with solid-phase microextraction (SPME), trace-level (part per trillion, 10

Indexed as

covalent organic frameworksextractionsynthetic cannabinoids

Identifiers

PMID37807813
PMCPMC10646270

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.