Evidence map›Paper›PMID 37807405›Full record

ReviewCurrent pharmaceutical biotechnology2024

An Exploration of Organoid Technology: Present Advancements, Applications, and Obstacles.

Isha Mishra, Komal Gupta, Raghav Mishra, Kajal Chaudhary, Vikram Sharma

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current pharmaceutical biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Isha MishraDepartment of Pharmacy, Galgotias College of Pharmacy, Greater Noida, Uttar Pradesh, 201310, India.
Komal GuptaDepartment of Pharmacy, Galgotias College of Pharmacy, Greater Noida, Uttar Pradesh, 201310, India.ORCID 0000-0003-2296-3441
Raghav MishraDepartment of Pharmacy, GLA University, Mathura, 281406, Uttar Pradesh, India.ORCID 0000-0001-5269-2860
Kajal ChaudharyDepartment of Pharmacy, GLA University, Mathura, 281406, Uttar Pradesh, India.ORCID 0000-0002-6866-241X
Vikram SharmaDepartment of Pharmacy, Galgotias College of Pharmacy, Greater Noida, Uttar Pradesh, 201310, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOrganoids are

objectivesThis work examines the potential applications of organoid technology, as well as the challenges and future directions associated with its implementation. It aims to emphasize the pivotal role of organoids in disease modeling, drug discovery, developmental biology, precision medicine, and fundamental research.

methodsThe manuscript was put together by conducting a comprehensive literature review, which involved an in-depth evaluation of globally renowned scientific research databases.

resultsThe field of organoids has generated significant attention due to its potential applications in tissue development and disease modelling, as well as its implications for personalised medicine, drug screening, and cell-based therapies. The utilisation of organoids has proven to be effective in the examination of various conditions, encompassing genetic disorders, cancer, neurodevelopmental disorders, and infectious diseases.

conclusionThe exploration of the wider uses of organoids is still in its early phases. Research shall be conducted to integrate 3D organoid systems as alternatives for current models, potentially improving both fundamental and clinical studies in the future.

Indexed as

OrganoidsPrecision MedicineAnimalsDrug DiscoveryHumansModels, Biologicaldisease modellingdrug screening.germ layerin vitro modelsOrganoidspersonalized medicinestem cell

Identifiers

PMID37807405

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.