Evidence map›Paper›PMID 37806976›Full record

ArticleClinical and experimental nephrology2024

eGFR slope as a surrogate endpoint for end-stage kidney disease in patients with diabetes and eGFR > 30 mL/min/1.73 m

Yuka Sugawara, Eiichiro Kanda, Mitsuru Ohsugi, Kohjiro Ueki, Naoki Kashihara, Masaomi Nangaku

Open access · hybridAbstract read
In one paragraph

Article in Clinical and experimental nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Yuka SugawaraDivision of Nephrology and Endocrinology, The University of Tokyo, Tokyo, Japan.
Eiichiro KandaMedical Science, Kawasaki Medical School, Okayama, Japan.
Mitsuru OhsugiDepartment of Diabetes, Endocrinology and Metabolism, National Center for Global Health and Medicine, Tokyo, Japan.
Kohjiro UekiDepartment of Diabetes, Endocrinology and Metabolism, National Center for Global Health and Medicine, Tokyo, Japan.
Naoki KashiharaDepartment of Nephrology and Hypertension, Kawasaki Medical School, Okayama, Japan.
Masaomi NangakuDivision of Nephrology and Endocrinology, The University of Tokyo, Tokyo, Japan. mnangaku@m.u-tokyo.ac.jp.ORCID http://orcid.org/0000-0001-7401-2934
Kawasaki Medical School · JPNational Center for Global Health and Medicine · JPThe University of Tokyo · JPUniversity of Tokyo Hospital · JP

Funding

Japan Agency for Medical Research and Development 22mk0101172h0003
6 · The paper itself

Abstract

backgroundAn analysis of European and American individuals revealed that a reduction in estimated glomerular filtration rate (eGFR) slope by 0.5 to 1.0 mL/min/1.73 m

methodsUsing data from the Japan diabetes comprehensive database project based on an advanced electronic medical record system (J-DREAMS) cohort of 51,483 Japanese patients with diabetes and a baseline eGFR ≥ 30 mL/min/1.73 m

resultsSlower eGFR decline by 0.75 mL/min/1.73 m

conclusionWe found that changes in the eGFR slope were associated with ESKD risk in this population.

Indexed as

Diabetes MellitusKidney Failure, ChronicRenal Insufficiency, ChronicBiomarkersDisease ProgressionGlomerular Filtration RateHumansBiomarkersChronic kidney diseaseDiabetic kidney diseaseeGFR slopeSurrogate endpoint

Identifiers

PMID37806976
PMCPMC10808312
OpenAlexW4387440296

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.