Evidence map›Paper›PMID 37805544›Full record

ArticleScientific reports2023

Muscarinic receptor agonist-induced βPix binding to β-catenin promotes colon neoplasia.

Kunrong Cheng, Ahmed Chahdi, Shannon M Larabee, Mazen Tolaymat, Margaret H Sundel, Cinthia B Drachenberg, Min Zhan, Shien Hu, Anan H Said, Aaron C Shang and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. GlialeLife · 2026
    Article
  2. Review
  3. Cholinergic Mechanisms in Gastrointestinal Neoplasia.International journal of molecular sciences · 2024
    Review
  4. Guanine nucleotide exchange factors and colon neoplasia.Frontiers in cell and developmental biology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Kunrong ChengVA Maryland Healthcare System, Baltimore, MD, 21201, USA.
Ahmed ChahdiDepartment of Medicine, Division of Gastroenterology and Hepatology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Shannon M LarabeeDepartment of Surgery, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Mazen TolaymatDepartment of Medicine, Division of Gastroenterology and Hepatology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Margaret H SundelDepartment of Surgery, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Cinthia B DrachenbergDepartment of Pathology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Min ZhanDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Shien HuVA Maryland Healthcare System, Baltimore, MD, 21201, USA.
Anan H SaidDepartment of Medicine, Division of Gastroenterology and Hepatology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Aaron C ShangDepartment of Medicine, Division of Gastroenterology and Hepatology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Guofeng XieVA Maryland Healthcare System, Baltimore, MD, 21201, USA.
Madeline AlizadehThe Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, 20201, USA.
Natalia Sampaio MouraDepartment of Medicine, Division of Gastroenterology and Hepatology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Andrea C BaffordDepartment of Surgery, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Richelle T WilliamsDepartment of Surgery, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Nader N HannaDepartment of Surgery, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Jean-Pierre RaufmanVA Maryland Healthcare System, Baltimore, MD, 21201, USA. jraufman@som.umaryland.edu.ORCID http://orcid.org/0000-0002-6340-4382
University of Maryland, Baltimore · US

Funding

Research Training in Gastroenterology and HepatologyT32DK067872 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI RAUFMAN, JEAN-PIERRE · 2005 to 2024
$7.2M
Muscarinic Receptors Regulate Colon Cancer Stem Cell Function and InvasivenessI01BX004890 · VA · BALTIMORE VA MEDICAL CENTER · PI RAUFMAN, JEAN-PIERRE · 2021 to 2024
–
BLRD VA I01 BX004890NIDDK NIH HHS T32 DK067872
6 · The paper itself

Abstract

M

Indexed as

beta CateninColonic NeoplasmsAnimalsCyclooxygenase 2Gene Expression Regulation, NeoplasticHumansMiceMice, KnockoutReceptors, MuscarinicRho Guanine Nucleotide Exchange Factorsbeta CateninCyclooxygenase 2Receptors, MuscarinicRho Guanine Nucleotide Exchange Factors

Identifiers

PMID37805544
PMCPMC10560271
OpenAlexW4387422191

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.