Evidence map›Paper›PMID 37805461›Full record

ArticleBMC infectious diseases2023

Catheter-Related Bloodstream Infections among patients on maintenance haemodialysis: a cross-sectional study at a tertiary hospital in Ghana.

Bismark Opoku-Asare, Vincent Boima, Vincent Jessey Ganu, Elvis Aboagye, Olive Asafu-Adjaye, Anita Ago Asare, Isaac Kyeremateng, Edward Kwakyi, Adwoa Agyei, Eric Sampane-Donkor and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Bismark Opoku-AsareDepartment of Medicine, Korle Bu Teaching Hospital, Accra, Ghana.
Vincent BoimaDepartment of Medicine, Korle Bu Teaching Hospital, Accra, Ghana.
Vincent Jessey GanuDepartment of Medicine, Korle Bu Teaching Hospital, Accra, Ghana.
Elvis AboagyeWest African Centre for Cell Biology of Infectious Pathogens, University of Ghana, Accra, Ghana.
Olive Asafu-AdjayeGreater Accra Regional Hospital, Accra, Ghana.
Anita Ago AsareDepartment of Community Health, University of Ghana Medical School, Accra, Ghana.
Isaac KyerematengGhana Health Service, Accra, Ghana.
Edward KwakyiDepartment of Medicine, Korle Bu Teaching Hospital, Accra, Ghana.
Adwoa AgyeiDepartment of Medicine, Korle Bu Teaching Hospital, Accra, Ghana.
Eric Sampane-DonkorDepartment of Medical Microbiology, University of Ghana Medical School, Accra, Ghana.
Peter PuplampuDepartment of Medicine, Korle Bu Teaching Hospital, Accra, Ghana. pedpup2@gmail.com.
University of Ghana · GHKorle Bu Teaching Hospital · GHGhana Health Service · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCatheter-Related Bloodstream Infections (CRBSIs) are notable complications among patients receiving maintenance haemodialysis. However, data on the prevalence of CRBSIs is lacking. This study was conducted to determine the prevalence and factors associated with CRBSIs among patients receiving haemodialysis in the renal unit of the largest tertiary hospital in Ghana.

methodsA hospital-based cross-sectional study was conducted on patients receiving maintenance haemodialysis via central venous catheters (CVC) between September 2021 and April 2022. Multivariate analysis using logistic regression was used to determine the risk factors that were predictive of CRBSI. Analysis was performed using SPSS version 23 and a p-value<0.05 was statistically significant.

resultsThe prevalence of CRBSI was 34.2% (52/152). Of these, more than half of them (53.9%(28/52)) had Possible CRBSI while 11.5% (6/52) had Definite CRBSI. Among the positive cultures, 62% (21/34) were from catheter sites whilst the rest were from peripheral blood. Gram-negative cultures made up 53% (18/34) of positive cultures with the rest being Gram positive cultures. Acinetobacter baumannii (33.3% (6/18)) was the commonest organism isolated among Gram-negative cultures whilst Coagulase negative Staphylococci (43.7% (7/16)) was the commonest organism isolated among Gram-positve cultures. Gram-negative bacilli were more predominant in this study making up 52.9% of the total bacteria cultured. Sex, duration of maintenance dialysis, underlying cause of End-stage kidney disease, mean corpuscular haemoglobin (MCH), neutrophil count and lymphocyte count were significantly predictive of CRBSI status (p<0.05).

conclusionThere was a high prevalence of CRBSI among patients undergoing haemodialysis. The commonest causative agent was Coagulase negative Staphylococci, however there was a predominance of Gram-negative bacilli as compared to Gram positive cocci. There is a need to set up infection surveillance unit in the renal unit to track CRBSI and put in place measures to reduce these CRBSI.

Indexed as

BacteremiaCatheter-Related InfectionsCentral Venous CathetersCoagulaseCross-Sectional StudiesGhanaGram-Negative BacteriaHumansRenal DialysisStaphylococcusTertiary Care CentersCoagulaseCatheter-related bloodstream infectionsCentral venous catheterHaemodialysis

Identifiers

PMID37805461
PMCPMC10559469
OpenAlexW4387428209

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.